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The present and future of PI3K inhibitors for cancer therapy.
Castel P, Toska E, Engelman JA, Scaltriti M. Castel P, et al. Among authors: engelman ja. Nat Cancer. 2021 Jun;2(6):587-597. doi: 10.1038/s43018-021-00218-4. Epub 2021 Jun 17. Nat Cancer. 2021. PMID: 35118422 Free PMC article.
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Engelman JA, et al. Nat Med. 2008 Dec;14(12):1351-6. doi: 10.1038/nm.1890. Epub 2008 Nov 30. Nat Med. 2008. PMID: 19029981 Free PMC article.
Targeting the PI3K signaling pathway in cancer.
Wong KK, Engelman JA, Cantley LC. Wong KK, et al. Among authors: engelman ja. Curr Opin Genet Dev. 2010 Feb;20(1):87-90. doi: 10.1016/j.gde.2009.11.002. Epub 2009 Dec 16. Curr Opin Genet Dev. 2010. PMID: 20006486 Free PMC article. Review.
The PI3K pathway as drug target in human cancer.
Courtney KD, Corcoran RB, Engelman JA. Courtney KD, et al. Among authors: engelman ja. J Clin Oncol. 2010 Feb 20;28(6):1075-83. doi: 10.1200/JCO.2009.25.3641. Epub 2010 Jan 19. J Clin Oncol. 2010. PMID: 20085938 Free PMC article. Review.
PIKing the right patient.
Turke AB, Engelman JA. Turke AB, et al. Among authors: engelman ja. Clin Cancer Res. 2010 Jul 15;16(14):3523-5. doi: 10.1158/1078-0432.CCR-10-1201. Epub 2010 Jun 10. Clin Cancer Res. 2010. PMID: 20538763
229 results