Wan L - Search Results

1

Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.

Shen M, Wei Y, Kim H, Wan L, Jiang YZ, Hang X, Raba M, Remiszewski S, Rowicki M, Wu CG, Wu S, Zhang L, Lu X, Yuan M, Smith HA, Zheng A, Bertino J, Jin JF, Xing Y, Shao ZM, Kang Y. Shen M, et al. Among authors: wan l. Nat Cancer. 2022 Jan;3(1):43-59. doi: 10.1038/s43018-021-00279-5. Epub 2021 Nov 29. Nat Cancer. 2022. PMID: 35121987 Free PMC article.

2

Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer.

Wan L, Kang Y. Wan L, et al. Adv Cancer Res. 2013;120:113-34. doi: 10.1016/B978-0-12-401676-7.00004-8. Adv Cancer Res. 2013. PMID: 23889989 Review.

3

Tumor metastasis: moving new biological insights into the clinic.

Wan L, Pantel K, Kang Y. Wan L, et al. Nat Med. 2013 Nov;19(11):1450-64. doi: 10.1038/nm.3391. Nat Med. 2013. PMID: 24202397 Review.

4

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.

Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, Xing Y, Kang Y. Wan L, et al. Cancer Cell. 2014 Jul 14;26(1):92-105. doi: 10.1016/j.ccr.2014.04.027. Epub 2014 Jun 26. Cancer Cell. 2014. PMID: 24981741 Free PMC article.

5

Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis.

Wan L, Hu G, Wei Y, Yuan M, Bronson RT, Yang Q, Siddiqui J, Pienta KJ, Kang Y. Wan L, et al. Cancer Res. 2014 Sep 15;74(18):5336-47. doi: 10.1158/0008-5472.CAN-14-1349. Epub 2014 Jul 29. Cancer Res. 2014. PMID: 25074613 Free PMC article.

6

Structural insights into the tumor-promoting function of the MTDH-SND1 complex.

Guo F, Wan L, Zheng A, Stanevich V, Wei Y, Satyshur KA, Shen M, Lee W, Kang Y, Xing Y. Guo F, et al. Among authors: wan l. Cell Rep. 2014 Sep 25;8(6):1704-1713. doi: 10.1016/j.celrep.2014.08.033. Epub 2014 Sep 18. Cell Rep. 2014. PMID: 25242325 Free PMC article.

7

Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.

Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin JF, Jaschinski F, Zhou T, Klar R, Kang Y. Shen M, et al. Among authors: wan l. Cancer Res. 2021 Feb 15;81(4):1014-1025. doi: 10.1158/0008-5472.CAN-20-1876. Epub 2020 Nov 25. Cancer Res. 2021. PMID: 33239430 Free PMC article.

8

Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer.

Shen M, Smith HA, Wei Y, Jiang YZ, Zhao S, Wang N, Rowicki M, Tang Y, Hang X, Wu S, Wan L, Shao ZM, Kang Y. Shen M, et al. Among authors: wan l. Nat Cancer. 2022 Jan;3(1):60-74. doi: 10.1038/s43018-021-00280-y. Epub 2021 Nov 29. Nat Cancer. 2022. PMID: 35121988 Free PMC article.

9

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X. Wan L, et al. Nature. 2017 Mar 9;543(7644):265-269. doi: 10.1038/nature21687. Epub 2017 Mar 1. Nature. 2017. PMID: 28241141 Free PMC article.

10

Impaired cell fate through gain-of-function mutations in a chromatin reader.

Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll TS, Li Y, Feng L, Chen G, Wang SP, Ortiz MV, Daley SK, Wang X, Xuan H, Kentsis A, Muir TW, Roeder RG, Li H, Li W, Tjian R, Wen H, Allis CD. Wan L, et al. Nature. 2020 Jan;577(7788):121-126. doi: 10.1038/s41586-019-1842-7. Epub 2019 Dec 18. Nature. 2020. PMID: 31853060 Free PMC article.

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