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Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation.
RSC Chem Biol. 2021 Oct 21;3(1):56-68. doi: 10.1039/d1cb00145k. eCollection 2022 Jan 5.
RSC Chem Biol. 2021.
PMID: 35128409
Free PMC article.
Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation.
Hubler Z, Friedrich RM, Sax JL, Allimuthu D, Gao F, Rivera-León AM, Pleshinger MJ, Bederman I, Adams DJ.
Hubler Z, et al. Among authors: pleshinger mj.
Cell Chem Biol. 2021 Jun 17;28(6):866-875.e5. doi: 10.1016/j.chembiol.2021.01.025. Epub 2021 Feb 25.
Cell Chem Biol. 2021.
PMID: 33636107
Free PMC article.
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Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa.
Silvaroli JA, Pleshinger MJ, Banerjee S, Kiser PD, Golczak M.
Silvaroli JA, et al. Among authors: pleshinger mj.
ACS Chem Biol. 2017 Sep 15;12(9):2296-2304. doi: 10.1021/acschembio.7b00336. Epub 2017 Jul 26.
ACS Chem Biol. 2017.
PMID: 28708375
Free PMC article.
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