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Page 1
Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults.
Jongo SA, Church LWP, Nchama VUNN, Hamad A, Chuquiyauri R, Kassim KR, Athuman T, Deal A, Natasha KC, Mtoro A, Mpina M, Nyakarungu E, Bidjimi GO, Owono MA, Mayé ERM, Mangue MEO, Okomo GNN, Pasialo BEN, Mandumbi DMO, Mikue MAL, Mochomuemue FL, Obono MO, Besahá JCM, Bijeri JR, Abegue GM, Veri YR, Bela IT, Chochi FC, Lima Sánchez JE, Pencelli V, Gayozo G, Nlang JAEM, Schindler T, James ER, Abebe Y, Lemiale L, Stabler TC, Murshedkar T, Chen MC, Schwabe C, Ratsirarson J, Rivas MR, Ayekaba MO, Milang DVN, Falla CC, Phiri WP, García GA, Maas CD, Nlavo BM, Tanner M, Billingsley PF, Kim Lee Sim B, Daubenberger C, Hoffman SL, Abdulla S, Richie TL. Jongo SA, et al. Among authors: james er. Am J Trop Med Hyg. 2022 Feb 7;106(4):1215-1226. doi: 10.4269/ajtmh.21-0942. Print 2022 Apr 6. Am J Trop Med Hyg. 2022. PMID: 35130487 Free PMC article.
Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria.
Hoffman SL, Billingsley PF, James E, Richman A, Loyevsky M, Li T, Chakravarty S, Gunasekera A, Chattopadhyay R, Li M, Stafford R, Ahumada A, Epstein JE, Sedegah M, Reyes S, Richie TL, Lyke KE, Edelman R, Laurens MB, Plowe CV, Sim BK. Hoffman SL, et al. Hum Vaccin. 2010 Jan;6(1):97-106. doi: 10.4161/hv.6.1.10396. Epub 2010 Jan 21. Hum Vaccin. 2010. PMID: 19946222 Review.
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity.
Epstein JE, Tewari K, Lyke KE, Sim BK, Billingsley PF, Laurens MB, Gunasekera A, Chakravarty S, James ER, Sedegah M, Richman A, Velmurugan S, Reyes S, Li M, Tucker K, Ahumada A, Ruben AJ, Li T, Stafford R, Eappen AG, Tamminga C, Bennett JW, Ockenhouse CF, Murphy JR, Komisar J, Thomas N, Loyevsky M, Birkett A, Plowe CV, Loucq C, Edelman R, Richie TL, Seder RA, Hoffman SL. Epstein JE, et al. Among authors: james er. Science. 2011 Oct 28;334(6055):475-80. doi: 10.1126/science.1211548. Epub 2011 Sep 8. Science. 2011. PMID: 21903775 Clinical Trial.
Controlled human malaria infections by intradermal injection of cryopreserved Plasmodium falciparum sporozoites.
Roestenberg M, Bijker EM, Sim BKL, Billingsley PF, James ER, Bastiaens GJH, Teirlinck AC, Scholzen A, Teelen K, Arens T, van der Ven AJAM, Gunasekera A, Chakravarty S, Velmurugan S, Hermsen CC, Sauerwein RW, Hoffman SL. Roestenberg M, et al. Among authors: james er. Am J Trop Med Hyg. 2013 Jan;88(1):5-13. doi: 10.4269/ajtmh.2012.12-0613. Epub 2012 Nov 13. Am J Trop Med Hyg. 2013. PMID: 23149582 Free PMC article. Clinical Trial.
Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.
Sheehy SH, Spencer AJ, Douglas AD, Sim BK, Longley RJ, Edwards NJ, Poulton ID, Kimani D, Williams AR, Anagnostou NA, Roberts R, Kerridge S, Voysey M, James ER, Billingsley PF, Gunasekera A, Lawrie AM, Hoffman SL, Hill AV. Sheehy SH, et al. Among authors: james er. PLoS One. 2013 Jun 18;8(6):e65960. doi: 10.1371/journal.pone.0065960. Print 2013. PLoS One. 2013. PMID: 23823332 Free PMC article.
Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.
Shekalaghe S, Rutaihwa M, Billingsley PF, Chemba M, Daubenberger CA, James ER, Mpina M, Ali Juma O, Schindler T, Huber E, Gunasekera A, Manoj A, Simon B, Saverino E, Church LWP, Hermsen CC, Sauerwein RW, Plowe C, Venkatesan M, Sasi P, Lweno O, Mutani P, Hamad A, Mohammed A, Urassa A, Mzee T, Padilla D, Ruben A, Sim BKL, Tanner M, Abdulla S, Hoffman SL. Shekalaghe S, et al. Among authors: james er. Am J Trop Med Hyg. 2014 Sep;91(3):471-480. doi: 10.4269/ajtmh.14-0119. Epub 2014 Jul 28. Am J Trop Med Hyg. 2014. PMID: 25070995 Free PMC article. Clinical Trial.
Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.
Hodgson SH, Juma E, Salim A, Magiri C, Kimani D, Njenga D, Muia A, Cole AO, Ogwang C, Awuondo K, Lowe B, Munene M, Billingsley PF, James ER, Gunasekera A, Sim BK, Njuguna P, Rampling TW, Richman A, Abebe Y, Kamuyu G, Muthui M, Elias SC, Molyneux S, Gerry S, Macharia A, Williams TN, Bull PC, Hill AV, Osier FH, Draper SJ, Bejon P, Hoffman SL, Ogutu B, Marsh K. Hodgson SH, et al. Among authors: james er. Front Microbiol. 2014 Dec 12;5:686. doi: 10.3389/fmicb.2014.00686. eCollection 2014. Front Microbiol. 2014. PMID: 25566206 Free PMC article.
Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.
Obiero JM, Shekalaghe S, Hermsen CC, Mpina M, Bijker EM, Roestenberg M, Teelen K, Billingsley PF, Sim BK, James ER, Daubenberger CA, Hoffman SL, Abdulla S, Sauerwein RW, Scholzen A. Obiero JM, et al. Among authors: james er. Infect Immun. 2015 May;83(5):2185-96. doi: 10.1128/IAI.03069-14. Epub 2015 Mar 16. Infect Immun. 2015. PMID: 25776749 Free PMC article. Clinical Trial.
193 results