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Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
Kuo SH, Tasset I, Cheng MM, Diaz A, Pan MK, Lieberman OJ, Hutten SJ, Alcalay RN, Kim S, Ximénez-Embún P, Fan L, Kim D, Ko HS, Yacoubian T, Kanter E, Liu L, Tang G, Muñoz J, Sardi SP, Li A, Gan L, Cuervo AM, Sulzer D. Kuo SH, et al. Among authors: cuervo am. Sci Adv. 2022 Feb 11;8(6):eabm6393. doi: 10.1126/sciadv.abm6393. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138901 Free article.
Chaperone-mediated autophagy in aging and disease.
Massey AC, Zhang C, Cuervo AM. Massey AC, et al. Among authors: cuervo am. Curr Top Dev Biol. 2006;73:205-35. doi: 10.1016/S0070-2153(05)73007-6. Curr Top Dev Biol. 2006. PMID: 16782460 Review.
Autophagy and neurodegeneration.
Ventruti A, Cuervo AM. Ventruti A, et al. Among authors: cuervo am. Curr Neurol Neurosci Rep. 2007 Sep;7(5):443-51. doi: 10.1007/s11910-007-0068-5. Curr Neurol Neurosci Rep. 2007. PMID: 17764636 Review.
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, Cuervo AM. Martinez-Vicente M, et al. Among authors: cuervo am. J Clin Invest. 2008 Feb;118(2):777-88. doi: 10.1172/JCI32806. J Clin Invest. 2008. PMID: 18172548 Free PMC article.
Methods to monitor chaperone-mediated autophagy.
Kaushik S, Cuervo AM. Kaushik S, et al. Among authors: cuervo am. Methods Enzymol. 2009;452:297-324. doi: 10.1016/S0076-6879(08)03619-7. Methods Enzymol. 2009. PMID: 19200890 Free PMC article.
300 results