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Page 1
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.
Hezaveh K, Shinde RS, Klötgen A, Halaby MJ, Lamorte S, Ciudad MT, Quevedo R, Neufeld L, Liu ZQ, Jin R, Grünwald BT, Foerster EG, Chaharlangi D, Guo M, Makhijani P, Zhang X, Pugh TJ, Pinto DM, Co IL, McGuigan AP, Jang GH, Khokha R, Ohashi PS, O'Kane GM, Gallinger S, Navarre WW, Maughan H, Philpott DJ, Brooks DG, McGaha TL. Hezaveh K, et al. Among authors: makhijani p. Immunity. 2022 Feb 8;55(2):324-340.e8. doi: 10.1016/j.immuni.2022.01.006. Immunity. 2022. PMID: 35139353 Free PMC article.
Chronic inflammation and the hallmarks of aging.
Baechle JJ, Chen N, Makhijani P, Winer S, Furman D, Winer DA. Baechle JJ, et al. Among authors: makhijani p. Mol Metab. 2023 Aug;74:101755. doi: 10.1016/j.molmet.2023.101755. Epub 2023 Jun 15. Mol Metab. 2023. PMID: 37329949 Free PMC article. Review.
Regulation of the immune system by the insulin receptor in health and disease.
Makhijani P, Basso PJ, Chan YT, Chen N, Baechle J, Khan S, Furman D, Tsai S, Winer DA. Makhijani P, et al. Front Endocrinol (Lausanne). 2023 Mar 13;14:1128622. doi: 10.3389/fendo.2023.1128622. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36992811 Free PMC article. Review.
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight.
Wu F, Du H, Overbey E, Kim J, Makhijani P, Martin N, Lerner CA, Nguyen K, Baechle J, Valentino TR, Fuentealba M, Bartleson JM, Halaweh H, Winer S, Meydan C, Garrett-Bakelman F, Sayed N, Melov S, Muratani M, Gerencser AA, Kasler HG, Beheshti A, Mason CE, Furman D, Winer DA. Wu F, et al. Among authors: makhijani p. Nat Commun. 2024 Jun 11;15(1):4795. doi: 10.1038/s41467-023-42013-y. Nat Commun. 2024. PMID: 38862487 Free PMC article.
Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts.
Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA. Du H, et al. Among authors: makhijani p. bioRxiv [Preprint]. 2024 Nov 21:2024.11.18.623471. doi: 10.1101/2024.11.18.623471. bioRxiv. 2024. PMID: 39605579 Free PMC article. Preprint.
Single-cell transcriptomics reveals colonic immune perturbations during amyloid-β driven Alzheimer's disease in mice.
Makhijani P, Emani R, Aguirre CG, Mu WC, Rane A, Ng JHY, Valentino TR, Manwaring-Mueller M, Tan CR, Du H, Wu F, Khan S, Wilson KA, Winer S, Wang C, Mortha A, Furman D, Ellerby LM, Rojas OL, Andersen JK, Winer DA. Makhijani P, et al. bioRxiv [Preprint]. 2024 Jan 30:2024.01.27.573841. doi: 10.1101/2024.01.27.573841. bioRxiv. 2024. PMID: 38352325 Free PMC article. Preprint.
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