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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE. Simpson DS, et al. Among authors: norton rs. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. Immunity. 2022. PMID: 35139355 Free PMC article.
The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.
Kuang Z, Lewis RS, Curtis JM, Zhan Y, Saunders BM, Babon JJ, Kolesnik TB, Low A, Masters SL, Willson TA, Kedzierski L, Yao S, Handman E, Norton RS, Nicholson SE. Kuang Z, et al. Among authors: norton rs. J Cell Biol. 2010 Jul 12;190(1):129-41. doi: 10.1083/jcb.200912087. Epub 2010 Jul 5. J Cell Biol. 2010. PMID: 20603330 Free PMC article.
TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.
Lewis RS, Kolesnik TB, Kuang Z, D'Cruz AA, Blewitt ME, Masters SL, Low A, Willson T, Norton RS, Nicholson SE. Lewis RS, et al. Among authors: norton rs. J Immunol. 2011 Oct 1;187(7):3798-805. doi: 10.4049/jimmunol.1002993. Epub 2011 Aug 29. J Immunol. 2011. PMID: 21876038
Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.
Linossi EM, Chandrashekaran IR, Kolesnik TB, Murphy JM, Webb AI, Willson TA, Kedzierski L, Bullock AN, Babon JJ, Norton RS, Nicola NA, Nicholson SE. Linossi EM, et al. Among authors: norton rs. PLoS One. 2013 Aug 21;8(8):e70536. doi: 10.1371/journal.pone.0070536. eCollection 2013. PLoS One. 2013. PMID: 23990909 Free PMC article.
369 results