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Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents.
Balestri LJI, D'Agostino I, Rango E, Vagaggini C, Marchitiello R, Mariotti M, Casian A, Deodato D, Truglio GI, Orofino F, Sanguinetti M, Bugli F, Botta L, Dreassi E. Balestri LJI, et al. Among authors: dreassi e. Mol Divers. 2022 Dec;26(6):3399-3409. doi: 10.1007/s11030-022-10388-7. Epub 2022 Feb 10. Mol Divers. 2022. PMID: 35143033 Free PMC article.
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family.
Tintori C, Brai A, Dasso Lang MC, Deodato D, Greco AM, Bizzarri BM, Cascone L, Casian A, Zamperini C, Dreassi E, Crespan E, Maga G, Vanham G, Ceresola E, Canducci F, Ariën KK, Botta M. Tintori C, et al. Among authors: dreassi e. J Med Chem. 2016 Mar 24;59(6):2747-59. doi: 10.1021/acs.jmedchem.5b01979. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26898379 Free article.
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor.
Fallacara AL, Zamperini C, Podolski-Renić A, Dinić J, Stanković T, Stepanović M, Mancini A, Rango E, Iovenitti G, Molinari A, Bugli F, Sanguinetti M, Torelli R, Martini M, Maccari L, Valoti M, Dreassi E, Botta M, Pešić M, Schenone S. Fallacara AL, et al. Among authors: dreassi e. Cancers (Basel). 2019 Jun 19;11(6):848. doi: 10.3390/cancers11060848. Cancers (Basel). 2019. PMID: 31248184 Free PMC article.
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains.
Orofino F, Truglio GI, Fiorucci D, D'Agostino I, Borgini M, Poggialini F, Zamperini C, Dreassi E, Maccari L, Torelli R, Martini C, Bernabei M, Meis JF, Khandelwal NK, Prasad R, Sanguinetti M, Bugli F, Botta M. Orofino F, et al. Among authors: dreassi e. Int J Antimicrob Agents. 2020 Mar;55(3):105865. doi: 10.1016/j.ijantimicag.2019.105865. Epub 2019 Dec 20. Int J Antimicrob Agents. 2020. PMID: 31866465
AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma.
Molinari A, Iovenitti G, Mancini A, Gravina GL, Chebbi M, Caruana M, Vignaroli G, Orofino F, Rango E, Angelucci A, Dreassi E, Schenone S, Botta M. Molinari A, et al. Among authors: dreassi e. ACS Med Chem Lett. 2020 Mar 5;11(5):664-670. doi: 10.1021/acsmedchemlett.9b00538. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435368 Free PMC article.
DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins.
Brai A, Riva V, Saladini F, Zamperini C, Trivisani CI, Garbelli A, Pennisi C, Giannini A, Boccuto A, Bugli F, Martini M, Sanguinetti M, Zazzi M, Dreassi E, Botta M, Maga G. Brai A, et al. Among authors: dreassi e. Eur J Med Chem. 2020 Aug 15;200:112319. doi: 10.1016/j.ejmech.2020.112319. Epub 2020 May 7. Eur J Med Chem. 2020. PMID: 32446036 Free article.
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
Rango E, D'Antona L, Iovenitti G, Brai A, Mancini A, Zamperini C, Trivisani CI, Marianelli S, Fallacara AL, Molinari A, Cianciusi A, Schenone S, Perrotti N, Dreassi E, Botta M. Rango E, et al. Among authors: dreassi e. Eur J Med Chem. 2021 Nov 5;223:113653. doi: 10.1016/j.ejmech.2021.113653. Epub 2021 Jun 17. Eur J Med Chem. 2021. PMID: 34161866
128 results