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Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
Ma Z, He S, Yuan Y, Zhuang Z, Liu Y, Wang H, Chen J, Xu X, Ding C, Molodtsov V, Lin W, Robertson GT, Weiss WJ, Pulse M, Nguyen P, Duncan L, Doyle T, Ebright RH, Lynch AS. Ma Z, et al. Among authors: liu y. J Med Chem. 2022 Mar 24;65(6):4481-4495. doi: 10.1021/acs.jmedchem.1c02045. Epub 2022 Feb 17. J Med Chem. 2022. PMID: 35175750 Free PMC article.
Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Lin W, Mandal S, Degen D, Liu Y, Ebright YW, Li S, Feng Y, Zhang Y, Mandal S, Jiang Y, Liu S, Gigliotti M, Talaue M, Connell N, Das K, Arnold E, Ebright RH. Lin W, et al. Among authors: liu y, liu s. Mol Cell. 2017 Apr 20;66(2):169-179.e8. doi: 10.1016/j.molcel.2017.03.001. Epub 2017 Apr 6. Mol Cell. 2017. PMID: 28392175 Free PMC article.
Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, Ebright YW, Ebright RY, Sineva E, Gigliotti M, Srivastava A, Mandal S, Jiang Y, Liu Y, Yin R, Zhang Z, Eng ET, Thomas D, Donadio S, Zhang H, Zhang C, Kapanidis AN, Ebright RH. Lin W, et al. Among authors: liu y. Mol Cell. 2018 Apr 5;70(1):60-71.e15. doi: 10.1016/j.molcel.2018.02.026. Epub 2018 Mar 29. Mol Cell. 2018. PMID: 29606590 Free PMC article.
Structural and mechanistic basis of reiterative transcription initiation.
Liu Y, Yu L, Pukhrambam C, Winkelman JT, Firlar E, Kaelber JT, Zhang Y, Nickels BE, Ebright RH. Liu Y, et al. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2115746119. doi: 10.1073/pnas.2115746119. Proc Natl Acad Sci U S A. 2022. PMID: 35082149 Free PMC article.
Fractional Spinon Quasiparticles in Open-Shell Triangulene Spin-1/2 Chains.
Yuan Z, Zhang XY, Jiang Y, Qian X, Wang Y, Liu Y, Liu L, Liu X, Guan D, Li Y, Zheng H, Liu C, Jia J, Qin M, Liu PN, Li DY, Wang S. Yuan Z, et al. Among authors: liu y. J Am Chem Soc. 2025 Jan 28. doi: 10.1021/jacs.4c14712. Online ahead of print. J Am Chem Soc. 2025. PMID: 39874540
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