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Chronic lung allograft dysfunction is associated with an early increase of circulating cytotoxic CD4+CD57+ILT2+ T cells, selectively inhibited by the immune check-point HLA-G.
Brugière O, Mouren D, Trichereau J, Vallée A, Kuzniak I, Hirschi S, Renaud-Picard B, Reynaud-Gaubert M, Nieves A, Bunel V, Messika J, Demant X, Macey J, Le Pavec J, Dauriat G, Saint-Raymond C, Falque L, Mornex JF, Tissot A, Foureau A, Borgne Krams AL, Bousseau V, Magnan A, Picard C, Roux A, Carosella E, LeMaoult J, Rouas-Freiss N; COLT Consortium. Brugière O, et al. Among authors: borgne krams al. J Heart Lung Transplant. 2022 May;41(5):626-640. doi: 10.1016/j.healun.2022.01.013. Epub 2022 Jan 24. J Heart Lung Transplant. 2022. PMID: 35181243