Darpo B - Search Results

1

A Phase 1 Clinical Study Evaluating the Effects of Cenobamate on the QT Interval.

Darpo B, Sager PT, Xue H, Kamin M. Darpo B, et al. Clin Pharmacol Drug Dev. 2022 Apr;11(4):523-534. doi: 10.1002/cpdd.1077. Epub 2022 Feb 19. Clin Pharmacol Drug Dev. 2022. PMID: 35182037 Clinical Trial.

2

Revefenacin, a Long-Acting Muscarinic Antagonist, Does Not Prolong QT Interval in Healthy Subjects: Results of a Placebo- and Positive-Controlled Thorough QT Study.

Borin MT, Barnes CN, Darpo B, Pendyala S, Xue H, Bourdet DL. Borin MT, et al. Among authors: darpo b. Clin Pharmacol Drug Dev. 2020 Jan;9(1):130-139. doi: 10.1002/cpdd.732. Epub 2019 Aug 29. Clin Pharmacol Drug Dev. 2020. PMID: 31468714 Free PMC article. Clinical Trial.

3

Evaluation of the Potential for QTc Prolongation With Repeated Oral Doses of Fedratinib in Patients With Advanced Solid Tumors.

Ogasawara K, Xu C, Yin J, Darpo B, Carayannopoulos L, Xue H, Palmisano M, Krishna G. Ogasawara K, et al. Among authors: darpo b. Clin Pharmacol Drug Dev. 2021 Apr;10(4):366-375. doi: 10.1002/cpdd.850. Epub 2020 Jul 16. Clin Pharmacol Drug Dev. 2021. PMID: 32673446 Clinical Trial.

4

Electrophysiological and ECG Effects of Perhexiline, a Mixed Cardiac Ion Channel Inhibitor, Evaluated in Nonclinical Assays and in Healthy Subjects.

Midei MG, Darpo B, Ayers G, Brown R, Couderc JP, Daly W, Ferber G, Sager PT, Camm AJ. Midei MG, et al. Among authors: darpo b. J Clin Pharmacol. 2021 Dec;61(12):1606-1617. doi: 10.1002/jcph.1934. Epub 2021 Jul 20. J Clin Pharmacol. 2021. PMID: 34214210 Clinical Trial.

5

A Phase 1 Thorough QT/QTc Study of Therapeutic and Supratherapeutic Doses of Belumosudil in Healthy Subjects.

Schueller O, Lohmer L, Xue H, Darpo B, Patel J. Schueller O, et al. Among authors: darpo b. Clin Pharmacol Drug Dev. 2022 Oct;11(10):1221-1232. doi: 10.1002/cpdd.1142. Epub 2022 Jul 26. Clin Pharmacol Drug Dev. 2022. PMID: 35881051 Clinical Trial.

6

Thorough QT/QTc Evaluation of the Cardiac Safety of Secnidazole at Therapeutic and Supratherapeutic Doses in Healthy Individuals.

Darpo B, Xue H, Adetoro N, Matthews BG, Pentikis HS. Darpo B, et al. J Clin Pharmacol. 2018 Mar;58(3):286-293. doi: 10.1002/jcph.1014. Epub 2017 Oct 2. J Clin Pharmacol. 2018. PMID: 28967984 Free PMC article. Clinical Trial.

7

Evaluating Potential QT Effects of JNJ-54861911, a BACE Inhibitor in Single- and Multiple-Ascending Dose Studies, and a Thorough QT Trial With Additional Retrospective Confirmation, Using Concentration-QTc Analysis.

Timmers M, Sinha V, Darpo B, Smith B, Brown R, Xue H, Ferber G, Streffer J, Russu A, Tritsmans L, Solanki B, Bogert J, Van Nueten L, Salvadore G, Nandy P. Timmers M, et al. Among authors: darpo b. J Clin Pharmacol. 2018 Jul;58(7):952-964. doi: 10.1002/jcph.1087. Epub 2018 Mar 5. J Clin Pharmacol. 2018. PMID: 29505101 Clinical Trial.

8

Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Omadacycline on QT/QTc Intervals in Healthy Subjects.

Darpo B, Xue H, Tanaka SK, Tzanis E. Darpo B, et al. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00922-19. doi: 10.1128/AAC.00922-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31405867 Free PMC article. Clinical Trial.

9

No QTc Prolongation With Zanubrutinib: Results of Concentration-QTc Analysis From a Thorough QT Study in Healthy Subjects.

Mu S, Darpo B, Tang Z, Novotny W, Tawashi M, Xue H, Willett M, Lin L, Sahasranaman S, Ou YC. Mu S, et al. Among authors: darpo b. Clin Transl Sci. 2020 Sep;13(5):923-931. doi: 10.1111/cts.12779. Epub 2020 Apr 8. Clin Transl Sci. 2020. PMID: 32144955 Free PMC article. Clinical Trial.

10

Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK-906), a Novel Selective D₂ /D₃ Receptor Antagonist: A Phase 1 Randomized, Placebo-Controlled Single- and Multiple-Dose Escalation Study in Healthy Participants.

Whiting RL, Darpo B, Chen C, Fletcher M, Combs D, Xue H, Stoltz RR. Whiting RL, et al. Among authors: darpo b. Clin Pharmacol Drug Dev. 2021 Aug;10(8):927-939. doi: 10.1002/cpdd.906. Epub 2021 Jan 18. Clin Pharmacol Drug Dev. 2021. PMID: 33462988 Free PMC article. Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

131 results

Search Page

Filters