Hartmann RW - Search Results

1

N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.

Kaya C, Konstantinović J, Kany AM, Andreas A, Kramer JS, Brunst S, Weizel L, Rotter MJ, Frank D, Yahiaoui S, Müller R, Hartmann RW, Haupenthal J, Proschak E, Wichelhaus TA, Hirsch AKH. Kaya C, et al. Among authors: hartmann rw. J Med Chem. 2022 Mar 10;65(5):3913-3922. doi: 10.1021/acs.jmedchem.1c01755. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188771

2

Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2.

Hartmann RW, Hector M, Haidar S, Ehmer PB, Reichert W, Jose J. Hartmann RW, et al. J Med Chem. 2000 Nov 2;43(22):4266-77. doi: 10.1021/jm001008m. J Med Chem. 2000. PMID: 11063622

3

Synthesis and evaluation of 2'-substituted 4-(4'-carboxy- or 4'-carboxymethylbenzylidene)-N-acylpiperidines: highly potent and in vivo active steroid 5alpha-reductase type 2 inhibitors.

Picard F, Barassin S, Mokhtarian A, Hartmann RW. Picard F, et al. Among authors: hartmann rw. J Med Chem. 2002 Aug 1;45(16):3406-17. doi: 10.1021/jm0208471. J Med Chem. 2002. PMID: 12139451

4

Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase.

Ulmschneider S, Müller-Vieira U, Klein CD, Antes I, Lengauer T, Hartmann RW. Ulmschneider S, et al. Among authors: hartmann rw. J Med Chem. 2005 Mar 10;48(5):1563-75. doi: 10.1021/jm0492397. J Med Chem. 2005. PMID: 15743198

5

Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase.

Ulmschneider S, Müller-Vieira U, Mitrenga M, Hartmann RW, Oberwinkler-Marchais S, Klein CD, Bureik M, Bernhardt R, Antes I, Lengauer T. Ulmschneider S, et al. Among authors: hartmann rw. J Med Chem. 2005 Mar 24;48(6):1796-805. doi: 10.1021/jm049600p. J Med Chem. 2005. PMID: 15771425

6

Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis.

Voets M, Antes I, Scherer C, Müller-Vieira U, Biemel K, Barassin C, Marchais-Oberwinkler S, Hartmann RW. Voets M, et al. Among authors: hartmann rw. J Med Chem. 2005 Oct 20;48(21):6632-42. doi: 10.1021/jm0503704. J Med Chem. 2005. PMID: 16220979

7

Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2).

Ulmschneider S, Negri M, Voets M, Hartmann RW. Ulmschneider S, et al. Among authors: hartmann rw. Bioorg Med Chem Lett. 2006 Jan 1;16(1):25-30. doi: 10.1016/j.bmcl.2005.09.059. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246562

8

Novel 5alpha-reductase inhibitors: synthesis, structure-activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids.

Salem OI, Frotscher M, Scherer C, Neugebauer A, Biemel K, Streiber M, Maas R, Hartmann RW. Salem OI, et al. Among authors: hartmann rw. J Med Chem. 2006 Jan 26;49(2):748-59. doi: 10.1021/jm050728w. J Med Chem. 2006. PMID: 16420060

9

Prediction of protein-protein interaction inhibitors by chemoinformatics and machine learning methods.

Neugebauer A, Hartmann RW, Klein CD. Neugebauer A, et al. Among authors: hartmann rw. J Med Chem. 2007 Sep 20;50(19):4665-8. doi: 10.1021/jm070533j. Epub 2007 Aug 17. J Med Chem. 2007. PMID: 17705363

10

Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure.

Jagusch C, Negri M, Hille UE, Hu Q, Bartels M, Jahn-Hoffmann K, Pinto-Bazurco Mendieta MA, Rodenwaldt B, Müller-Vieira U, Schmidt D, Lauterbach T, Recanatini M, Cavalli A, Hartmann RW. Jagusch C, et al. Among authors: hartmann rw. Bioorg Med Chem. 2008 Feb 15;16(4):1992-2010. doi: 10.1016/j.bmc.2007.10.094. Epub 2007 Nov 4. Bioorg Med Chem. 2008. PMID: 18061460

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

346 results

Search Page

Filters