Xu Z - Search Results

1

Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice.

Gu X, Hu X, Wang D, Xu Z, Wang F, Li D, Li GL, Yang H, Li H, Zuo E, Shu Y. Gu X, et al. Among authors: xu z. Cell Res. 2022 Jul;32(7):699-702. doi: 10.1038/s41422-022-00624-y. Epub 2022 Feb 23. Cell Res. 2022. PMID: 35197607 Free PMC article. No abstract available.

2

Prevention of acquired sensorineural hearing loss in mice by in vivo Htra2 gene editing.

Gu X, Wang D, Xu Z, Wang J, Guo L, Chai R, Li G, Shu Y, Li H. Gu X, et al. Among authors: xu z. Genome Biol. 2021 Mar 22;22(1):86. doi: 10.1186/s13059-021-02311-4. Genome Biol. 2021. PMID: 33752742 Free PMC article.

3

Gene editing in a Myo6 semi-dominant mouse model rescues auditory function.

Xue Y, Hu X, Wang D, Li D, Li Y, Wang F, Huang M, Gu X, Xu Z, Zhou J, Wang J, Chai R, Shen J, Chen ZY, Li GL, Yang H, Li H, Zuo E, Shu Y. Xue Y, et al. Among authors: xu z. Mol Ther. 2022 Jan 5;30(1):105-118. doi: 10.1016/j.ymthe.2021.06.015. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174443 Free PMC article.

4

Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing.

Zheng Z, Li G, Cui C, Wang F, Wang X, Xu Z, Guo H, Chen Y, Tang H, Wang D, Huang M, Chen ZY, Huang X, Li H, Li GL, Hu X, Shu Y. Zheng Z, et al. Among authors: xu z. Signal Transduct Target Ther. 2022 Mar 14;7(1):79. doi: 10.1038/s41392-022-00893-4. Signal Transduct Target Ther. 2022. PMID: 35283480 Free PMC article.

5

Rescue of mis-splicing of a common SLC26A4 mutant associated with sensorineural hearing loss by antisense oligonucleotides.

Feng P, Xu Z, Chen J, Liu M, Zhao Y, Wang D, Han L, Wang L, Wan B, Xu X, Li D, Shu Y, Hua Y. Feng P, et al. Among authors: xu x, xu z. Mol Ther Nucleic Acids. 2022 Mar 19;28:280-292. doi: 10.1016/j.omtn.2022.03.015. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35433113 Free PMC article.

6

Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor.

Xiao Q, Xu Z, Xue Y, Xu C, Han L, Liu Y, Wang F, Zhang R, Han S, Wang X, Li GL, Li H, Yang H, Shu Y. Xiao Q, et al. Among authors: xu c, xu z. Sci Transl Med. 2022 Jul 20;14(654):eabn0449. doi: 10.1126/scitranslmed.abn0449. Epub 2022 Jul 20. Sci Transl Med. 2022. PMID: 35857824

7

Distributional comparison of different AAV vectors after unilateral cochlear administration.

Han S, Xu Z, Wang S, Tang H, Hu S, Wang H, Guan G, Shu Y. Han S, et al. Among authors: xu z. Gene Ther. 2024 Mar;31(3-4):154-164. doi: 10.1038/s41434-023-00431-z. Epub 2023 Dec 14. Gene Ther. 2024. PMID: 38097651

8

Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 system.

Qiu W, Xu Z, Zhang M, Zhang D, Fan H, Li T, Wang Q, Liu P, Zhu Z, Du D, Tan M, Wen B, Liu Y. Qiu W, et al. Among authors: xu z. Nucleic Acids Res. 2019 May 21;47(9):e52. doi: 10.1093/nar/gkz134. Nucleic Acids Res. 2019. PMID: 30805613 Free PMC article.

9

Concurrent DNA hypomethylation and epigenomic reprogramming driven by androgen receptor binding in bladder cancer oncogenesis.

Xiao Y, Ju L, Jin W, Peng H, Zhou Z, Yu M, Xu Z, Wang G, Qian K, Zhang Y, Wang X. Xiao Y, et al. Among authors: xu z. Clin Transl Med. 2025 Jan;15(1):e70153. doi: 10.1002/ctm2.70153. Clin Transl Med. 2025. PMID: 39731353 No abstract available.

10

Super-enhancer Activates Master Transcription Factor NR3C1 Expression and Promotes 5-FU Resistance in Gastric Cancer.

Yu J, Chen M, Sang Q, Li F, Xu Z, Yu B, He C, Su L, Dai W, Yan C, Zhu ZG, Xia J, Li J, Feng H, Chen Y, Li YY, Liu B. Yu J, et al. Among authors: xu z. Adv Sci (Weinh). 2024 Dec 27:e2409050. doi: 10.1002/advs.202409050. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39731339

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