Arnold E - Search Results

1

Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing.

Ruiz FX, Hoang A, Dilmore CR, DeStefano JJ, Arnold E. Ruiz FX, et al. Among authors: arnold e. Drug Discov Today. 2022 Jul;27(7):1832-1846. doi: 10.1016/j.drudis.2022.02.016. Epub 2022 Feb 23. Drug Discov Today. 2022. PMID: 35218925 Free PMC article. Review.

2

HIV-1 reverse transcriptase and antiviral drug resistance. Part 2.

Das K, Arnold E. Das K, et al. Among authors: arnold e. Curr Opin Virol. 2013 Apr;3(2):119-28. doi: 10.1016/j.coviro.2013.03.014. Epub 2013 Apr 19. Curr Opin Virol. 2013. PMID: 23602470 Free PMC article. Review.

3

HIV-1 reverse transcriptase and antiviral drug resistance. Part 1.

Das K, Arnold E. Das K, et al. Among authors: arnold e. Curr Opin Virol. 2013 Apr;3(2):111-8. doi: 10.1016/j.coviro.2013.03.012. Epub 2013 Apr 19. Curr Opin Virol. 2013. PMID: 23602471 Free PMC article. Review.

4

Structure of HIV-1 reverse transcriptase bound to a novel 38-mer hairpin template-primer DNA aptamer.

Miller MT, Tuske S, Das K, DeStefano JJ, Arnold E. Miller MT, et al. Among authors: arnold e. Protein Sci. 2016 Jan;25(1):46-55. doi: 10.1002/pro.2776. Epub 2015 Sep 18. Protein Sci. 2016. PMID: 26296781 Free PMC article.

5

Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.

Das K, Balzarini J, Miller MT, Maguire AR, DeStefano JJ, Arnold E. Das K, et al. Among authors: arnold e. ACS Chem Biol. 2016 Aug 19;11(8):2158-64. doi: 10.1021/acschembio.6b00187. Epub 2016 Jun 6. ACS Chem Biol. 2016. PMID: 27192549 Free PMC article.

6

Correction to Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.

Das K, Balzarini J, Miller MT, Maguire AR, DeStefano JJ, Arnold E. Das K, et al. Among authors: arnold e. ACS Chem Biol. 2016 Nov 18;11(11):3226. doi: 10.1021/acschembio.6b00798. Epub 2016 Sep 26. ACS Chem Biol. 2016. PMID: 27696816 No abstract available.

7

Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.

Das K, Martinez SE, Arnold E. Das K, et al. Among authors: arnold e. Antimicrob Agents Chemother. 2017 May 24;61(6):e00224-17. doi: 10.1128/AAC.00224-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28396546 Free PMC article.

8

Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation.

Das K, Martinez SE, DeStefano JJ, Arnold E. Das K, et al. Among authors: arnold e. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7308-7313. doi: 10.1073/pnas.1814170116. Epub 2019 Mar 22. Proc Natl Acad Sci U S A. 2019. PMID: 30902895 Free PMC article.

9

Epistasis and entrenchment of drug resistance in HIV-1 subtype B.

Biswas A, Haldane A, Arnold E, Levy RM. Biswas A, et al. Among authors: arnold e. Elife. 2019 Oct 8;8:e50524. doi: 10.7554/eLife.50524. Elife. 2019. PMID: 31591964 Free PMC article.

10

Structural Basis of HIV-1 Inhibition by Nucleotide-Competing Reverse Transcriptase Inhibitor INDOPY-1.

Ruiz FX, Hoang A, Das K, Arnold E. Ruiz FX, et al. Among authors: arnold e. J Med Chem. 2019 Nov 14;62(21):9996-10002. doi: 10.1021/acs.jmedchem.9b01289. Epub 2019 Oct 25. J Med Chem. 2019. PMID: 31603676 Free PMC article.

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