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Mucus, commensals, and the immune system.
Zhao Q, Maynard CL. Zhao Q, et al. Gut Microbes. 2022 Jan-Dec;14(1):2041342. doi: 10.1080/19490976.2022.2041342. Gut Microbes. 2022. PMID: 35239459 Free PMC article. Review.
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity.
Uzzan M, Martin JC, Mesin L, Livanos AE, Castro-Dopico T, Huang R, Petralia F, Magri G, Kumar S, Zhao Q, Rosenstein AK, Tokuyama M, Sharma K, Ungaro R, Kosoy R, Jha D, Fischer J, Singh H, Keir ME, Ramamoorthi N, O'Gorman WE, Cohen BL, Rahman A, Cossarini F, Seki A, Leyre L, Vaquero ST, Gurunathan S, Grasset EK, Losic B, Dubinsky M, Greenstein AJ, Gottlieb Z, Legnani P, George J, Irizar H, Stojmirovic A, Brodmerkel C, Kasarkis A, Sands BE, Furtado G, Lira SA, Tuong ZK, Ko HM, Cerutti A, Elson CO, Clatworthy MR, Merad M, Suárez-Fariñas M, Argmann C, Hackney JA, Victora GD, Randolph GJ, Kenigsberg E, Colombel JF, Mehandru S. Uzzan M, et al. Among authors: zhao q. Nat Med. 2022 Apr;28(4):766-779. doi: 10.1038/s41591-022-01680-y. Epub 2022 Feb 21. Nat Med. 2022. PMID: 35190725 Free PMC article.
Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes.
Zhao Q, Duck LW, Killian JT Jr, Rosenberg AF, Mannon PJ, King RG, Denson LA, Kugathasan S, Janoff EN, Jenmalm MC, Elson CO. Zhao Q, et al. bioRxiv [Preprint]. 2023 Aug 11:2023.08.08.552496. doi: 10.1101/2023.08.08.552496. bioRxiv. 2023. Update in: Gastroenterology. 2024 Dec;167(7):1415-1428. doi: 10.1053/j.gastro.2024.08.015 PMID: 37609309 Free PMC article. Updated. Preprint.
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