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Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants.
Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM. Ryan TE, et al. Among authors: schmidt ca. JCI Insight. 2018 Nov 2;3(21):e123235. doi: 10.1172/jci.insight.123235. JCI Insight. 2018. PMID: 30385731 Free PMC article.
Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation.
Iñigo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, Kilburg-Basnyat BB, Reece SW, Psaltis CE, Leinwand LA, Funai K, McClung JM, Gowdy KM, Witczak CA, Lowe DA, Neufer PD, Spangenburg EE. Iñigo MR, et al. Among authors: schmidt ca. Mol Metab. 2020 Apr;34:1-15. doi: 10.1016/j.molmet.2019.12.010. Epub 2019 Dec 23. Mol Metab. 2020. PMID: 32180550 Free PMC article.
PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb.
Ryan TE, Schmidt CA, Tarpey MD, Amorese AJ, Yamaguchi DJ, Goldberg EJ, Iñigo MM, Karnekar R, O'Rourke A, Ervasti JM, Brophy P, Green TD, Neufer PD, Fisher-Wellman K, Spangenburg EE, McClung JM. Ryan TE, et al. Among authors: schmidt ca. JCI Insight. 2020 Sep 17;5(18):e139628. doi: 10.1172/jci.insight.139628. JCI Insight. 2020. PMID: 32841216 Free PMC article.
280 results