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Page 1
Spatial and phenotypic immune profiling of metastatic colon cancer.
Lazarus J, Maj T, Smith JJ, Perusina Lanfranca M, Rao A, D'Angelica MI, Delrosario L, Girgis A, Schukow C, Shia J, Kryczek I, Shi J, Wasserman I, Crawford H, Nathan H, Pasca Di Magliano M, Zou W, Frankel TL. Lazarus J, et al. Among authors: frankel tl. JCI Insight. 2018 Nov 15;3(22):e121932. doi: 10.1172/jci.insight.121932. JCI Insight. 2018. PMID: 30429368 Free PMC article.
Mathematical Modeling of the Metastatic Colorectal Cancer Microenvironment Defines the Importance of Cytotoxic Lymphocyte Infiltration and Presence of PD-L1 on Antigen Presenting Cells.
Lazarus J, Oneka MD, Barua S, Maj T, Lanfranca MP, Delrosario L, Sun L, Smith JJ, D'Angelica MI, Shia J, Fang JM, Shi J, Di Magliano MP, Zou W, Rao A, Frankel TL. Lazarus J, et al. Among authors: frankel tl. Ann Surg Oncol. 2019 Sep;26(9):2821-2830. doi: 10.1245/s10434-019-07508-3. Epub 2019 Jun 27. Ann Surg Oncol. 2019. PMID: 31250346 Free PMC article.
Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, Syu L, Hao Y, Oni TE, Brosnan E, Elyada E, Doshi A, Hansma C, Espinoza C, Abbas A, The S, Irizarry-Negron V, Halbrook CJ, Franks NE, Hoffman MT, Brown K, Carpenter ES, Nwosu ZC, Johnson C, Lima F, Anderson MA, Park Y, Crawford HC, Lyssiotis CA, Frankel TL, Rao A, Bednar F, Dlugosz AA, Preall JB, Tuveson DA, Allen BL, Pasca di Magliano M. Steele NG, et al. Among authors: frankel tl. Clin Cancer Res. 2021 Apr 1;27(7):2023-2037. doi: 10.1158/1078-0432.CCR-20-3715. Epub 2021 Jan 25. Clin Cancer Res. 2021. PMID: 33495315 Free PMC article.
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Kemp SB, Steele NG, Carpenter ES, Donahue KL, Bushnell GG, Morris AH, The S, Orbach SM, Sirihorachai VR, Nwosu ZC, Espinoza C, Lima F, Brown K, Girgis AA, Gunchick V, Zhang Y, Lyssiotis CA, Frankel TL, Bednar F, Rao A, Sahai V, Shea LD, Crawford HC, Pasca di Magliano M. Kemp SB, et al. Among authors: frankel tl. Life Sci Alliance. 2021 Mar 29;4(6):e202000935. doi: 10.26508/lsa.202000935. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33782087 Free PMC article.
Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer.
Steele NG, Carpenter ES, Kemp SB, Sirihorachai VR, The S, Delrosario L, Lazarus J, Amir ED, Gunchick V, Espinoza C, Bell S, Harris L, Lima F, Irizarry-Negron V, Paglia D, Macchia J, Chu AKY, Schofield H, Wamsteker EJ, Kwon R, Schulman A, Prabhu A, Law R, Sondhi A, Yu J, Patel A, Donahue K, Nathan H, Cho C, Anderson MA, Sahai V, Lyssiotis CA, Zou W, Allen BL, Rao A, Crawford HC, Bednar F, Frankel TL, Pasca di Magliano M. Steele NG, et al. Among authors: frankel tl. Nat Cancer. 2020 Nov;1(11):1097-1112. doi: 10.1038/s43018-020-00121-4. Epub 2020 Oct 26. Nat Cancer. 2020. PMID: 34296197 Free PMC article.
Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming.
Velez-Delgado A, Donahue KL, Brown KL, Du W, Irizarry-Negron V, Menjivar RE, Lasse Opsahl EL, Steele NG, The S, Lazarus J, Sirihorachai VR, Yan W, Kemp SB, Kerk SA, Bollampally M, Yang S, Scales MK, Avritt FR, Lima F, Lyssiotis CA, Rao A, Crawford HC, Bednar F, Frankel TL, Allen BL, Zhang Y, Pasca di Magliano M. Velez-Delgado A, et al. Among authors: frankel tl. Cell Mol Gastroenterol Hepatol. 2022;13(6):1673-1699. doi: 10.1016/j.jcmgh.2022.02.016. Epub 2022 Mar 1. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35245687 Free PMC article.
105 results