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Large-scale design and refinement of stable proteins using sequence-only models.
Singer JM, Novotney S, Strickland D, Haddox HK, Leiby N, Rocklin GJ, Chow CM, Roy A, Bera AK, Motta FC, Cao L, Strauch EM, Chidyausiku TM, Ford A, Ho E, Zaitzeff A, Mackenzie CO, Eramian H, DiMaio F, Grigoryan G, Vaughn M, Stewart LJ, Baker D, Klavins E. Singer JM, et al. PLoS One. 2022 Mar 14;17(3):e0265020. doi: 10.1371/journal.pone.0265020. eCollection 2022. PLoS One. 2022. PMID: 35286324 Free PMC article.
The Role of Configurational Entropy in Miniprotein Stability.
Estrada Pabón JD, Haddox HK, Van Aken G, Pendleton IM, Eramian H, Singer JM, Schrier J. Estrada Pabón JD, et al. Among authors: singer jm. J Phys Chem B. 2021 Apr 1;125(12):3057-3065. doi: 10.1021/acs.jpcb.0c09888. Epub 2021 Mar 19. J Phys Chem B. 2021. PMID: 33739115
Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice.
LaPoint A, Singer JM, Ferguson D, Shew TM, Renkemeyer MK, Palacios HH, Field RL, Yerrathota S, Kumari R, Shankaran M, Smith GI, Yoshino J, He M, Patti GJ, Hellerstein MK, Klein S, Brestoff JR, Morris EM, Finck BN, Lutkewitte AJ. LaPoint A, et al. Among authors: singer jm. J Clin Invest. 2024 Oct 15;134(23):e169722. doi: 10.1172/JCI169722. J Clin Invest. 2024. PMID: 39405118 Free PMC article.
What do young people know about the nicotine in their e-cigarettes?
Balzer G, Landrus A, Ovestrud I, Singer JM, Lu B, Wagner DD, Klein EG, Wold LE, Wilson C, Tackett AP, Roberts ME. Balzer G, et al. Among authors: singer jm. Tob Control. 2023 Nov 16:tc-2023-058234. doi: 10.1136/tc-2023-058234. Online ahead of print. Tob Control. 2023. PMID: 37973361
154 results