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Evidence for spontaneous cannabinoid withdrawal in mice.
Paronis C, Iliopoulos-Tsoutsouvas C, Papanastasiou I, Makriyannis A, Bergman J, Nikas SP. Paronis C, et al. Among authors: papanastasiou i. Behav Pharmacol. 2022 Apr 1;33(2&3):184-194. doi: 10.1097/FBP.0000000000000665. Behav Pharmacol. 2022. PMID: 35288509 Free PMC article.
Novel 1',1'-chain substituted hexahydrocannabinols: 9β-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist.
Nikas SP, Alapafuja SO, Papanastasiou I, Paronis CA, Shukla VG, Papahatjis DP, Bowman AL, Halikhedkar A, Han X, Makriyannis A. Nikas SP, et al. Among authors: papanastasiou i. J Med Chem. 2010 Oct 14;53(19):6996-7010. doi: 10.1021/jm100641g. J Med Chem. 2010. PMID: 20925434 Free PMC article.
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists.
Papanastasiou IP, Georgiadis MO, Iliopoulos-Tsoutsouvas C, Paronis CA, Brust CA, Tran NK, Ji L, Ma X, Wood JT, Zvonok N, Tong F, Bohn LM, Nikas SP, Makriyannis A. Papanastasiou IP, et al. Eur J Med Chem. 2022 Feb 15;230:114027. doi: 10.1016/j.ejmech.2021.114027. Epub 2021 Dec 27. Eur J Med Chem. 2022. PMID: 35051750
[No title available]
[No authors listed] [No authors listed] PMID: 35556732
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A. Riganas S, et al. Among authors: papanastasiou i. J Med Chem. 2012 Nov 26;55(22):10241-61. doi: 10.1021/jm3013008. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23094992
Synthesis of diphenoxyadamantane alkylamines with pharmacological interest.
Georgiadis MO, Kourbeli V, Ioannidou V, Karakitsios E, Papanastasiou I, Tsotinis A, Komiotis D, Vocat A, Cole ST, Taylor MC, Kelly JM. Georgiadis MO, et al. Among authors: papanastasiou i. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1278-1281. doi: 10.1016/j.bmcl.2019.04.010. Epub 2019 Apr 6. Bioorg Med Chem Lett. 2019. PMID: 30981579
43 results