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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, Liu H, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Wilson IA, Safonova Y, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: musharrafieh r. bioRxiv [Preprint]. 2022 Mar 7:2022.03.04.479488. doi: 10.1101/2022.03.04.479488. bioRxiv. 2022. Update in: Immunity. 2023 Mar 14;56(3):669-686.e7. doi: 10.1016/j.immuni.2023.02.005 PMID: 35291291 Free PMC article. Updated. Preprint.
Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. He WT, et al. Among authors: musharrafieh r. bioRxiv [Preprint]. 2022 Feb 8:2021.09.08.459480. doi: 10.1101/2021.09.08.459480. bioRxiv. 2022. Update in: Nat Immunol. 2022 Jun;23(6):960-970. doi: 10.1038/s41590-022-01222-1 PMID: 35169804 Free PMC article. Updated. Preprint.
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes.
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B. Hurtado J, et al. Among authors: musharrafieh r. bioRxiv [Preprint]. 2023 Mar 31:2023.03.28.534602. doi: 10.1101/2023.03.28.534602. bioRxiv. 2023. Update in: Cell Rep. 2024 Jun 25;43(6):114307. doi: 10.1016/j.celrep.2024.114307 PMID: 37034676 Free PMC article. Updated. Preprint.
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Song G, Yuan M, Liu H, Capozzola T, Lin RN, Torres JL, He WT, Musharrafieh R, Dueker K, Zhou P, Callaghan S, Mishra N, Yong P, Anzanello F, Avillion G, Vo AL, Li X, Makhdoomi M, Feng Z, Zhu X, Peng L, Nemazee D, Safonova Y, Briney B, Ward AB, Burton DR, Wilson IA, Andrabi R. Song G, et al. Among authors: musharrafieh r. bioRxiv [Preprint]. 2023 Apr 27:2023.04.26.538488. doi: 10.1101/2023.04.26.538488. bioRxiv. 2023. PMID: 37162858 Free PMC article. Preprint.
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes.
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B. Hurtado J, et al. Among authors: musharrafieh r. Cell Rep. 2024 Jun 25;43(6):114307. doi: 10.1016/j.celrep.2024.114307. Epub 2024 Jun 5. Cell Rep. 2024. PMID: 38848216 Free PMC article.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Zhou P, Song G, Liu H, Yuan M, He WT, Beutler N, Zhu X, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Safonova Y, Briney B, Rogers TF, Wilson IA, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: musharrafieh r. Immunity. 2023 Mar 14;56(3):669-686.e7. doi: 10.1016/j.immuni.2023.02.005. Epub 2023 Feb 16. Immunity. 2023. PMID: 36889306 Free PMC article.
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R. He WT, et al. Among authors: musharrafieh r. Sci Transl Med. 2022 Aug 10;14(657):eabl9605. doi: 10.1126/scitranslmed.abl9605. Epub 2022 Aug 10. Sci Transl Med. 2022. PMID: 35947674 Free PMC article.
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. He WT, et al. Among authors: musharrafieh r. Nat Immunol. 2022 Jun;23(6):960-970. doi: 10.1038/s41590-022-01222-1. Epub 2022 Jun 2. Nat Immunol. 2022. PMID: 35654851 Free PMC article.
37 results