Mager DE - Search Results

1

Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.

Odunsi K, Qian F, Lugade AA, Yu H, Geller MA, Fling SP, Kaiser JC, Lacroix AM, D'Amico L, Ramchurren N, Morishima C, Disis ML, Dennis L, Danaher P, Warren S, Nguyen VA, Ravi S, Tsuji T, Rosario S, Zha W, Hutson A, Liu S, Lele S, Zsiros E, McGray AJR, Chiello J, Koya R, Chodon T, Morrison CD, Putluri V, Putluri N, Mager DE, Gunawan R, Cheever MA, Battaglia S, Matsuzaki J. Odunsi K, et al. Among authors: mager de. Sci Transl Med. 2022 Mar 16;14(636):eabg8402. doi: 10.1126/scitranslmed.abg8402. Epub 2022 Mar 16. Sci Transl Med. 2022. PMID: 35294258 Free PMC article.

2

Boolean network modeling in systems pharmacology.

Bloomingdale P, Nguyen VA, Niu J, Mager DE. Bloomingdale P, et al. Among authors: mager de. J Pharmacokinet Pharmacodyn. 2018 Feb;45(1):159-180. doi: 10.1007/s10928-017-9567-4. Epub 2018 Jan 6. J Pharmacokinet Pharmacodyn. 2018. PMID: 29307099 Free PMC article. Review.

3

Cluster Gauss-Newton and CellNOpt Parameter Estimation in a Small Protein Signaling Network of Vorinostat and Bortezomib Pharmacodynamics.

Niu J, Nguyen VA, Ghasemi M, Chen T, Mager DE. Niu J, et al. Among authors: mager de. AAPS J. 2021 Oct 7;23(6):110. doi: 10.1208/s12248-021-00640-7. AAPS J. 2021. PMID: 34622346 Free PMC article.

4

Target Reserve and Turnover Parameters Determine Rightward Shift of Enalaprilat Potency From its Binding Affinity to the Angiotensin Converting Enzyme.

Nguyen VA, Zhang L, Kagan L, Rowland M, Mager DE. Nguyen VA, et al. Among authors: mager de. J Pharm Sci. 2024 Jan;113(1):167-175. doi: 10.1016/j.xphs.2023.10.025. Epub 2023 Oct 21. J Pharm Sci. 2024. PMID: 37871777

5

Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non-small cell lung cancer.

Heineman T, Baumgart M, Nanavati C, Gabrail N, Van Wart SA, Mager DE, Maneval DC, Fathallah AM, Sekulovich RE. Heineman T, et al. Among authors: mager de. Clin Transl Sci. 2021 Sep;14(5):1875-1885. doi: 10.1111/cts.13041. Epub 2021 Jul 30. Clin Transl Sci. 2021. PMID: 33982408 Free PMC article. Clinical Trial.

6

Cell Signaling Model Connects Vorinostat Pharmacokinetics and Tumor Growth Response in Multiple Myeloma Xenografts.

Nanavati C, Ruszaj D, Mager DE. Nanavati C, et al. Among authors: mager de. CPT Pharmacometrics Syst Pharmacol. 2017 Nov;6(11):756-764. doi: 10.1002/psp4.12246. Epub 2017 Oct 17. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 29045072 Free PMC article.

7

Challenges with sirolimus experimental data to inform QSP model of post-transplantation cyclophosphamide regimens.

Mohanan E, Shen G, Ren S, Fan HH, Moua KTY, Karolak A, Rockne RC, Nakamura R, Horne DA, Kanakry CG, Mager DE, McCune JS. Mohanan E, et al. Among authors: mager de. Clin Transl Sci. 2024 Aug;17(8):e70014. doi: 10.1111/cts.70014. Clin Transl Sci. 2024. PMID: 39162578 Free PMC article. Review.

8

Pharmacokinetic/pharmacodynamic modeling of renin biomarkers in subjects treated with the renin inhibitor aliskiren.

Hong Y, Dingemanse J, Mager DE. Hong Y, et al. Among authors: mager de. Clin Pharmacol Ther. 2008 Jul;84(1):136-43. doi: 10.1038/sj.clpt.6100495. Epub 2008 Feb 20. Clin Pharmacol Ther. 2008. PMID: 18288088

9

Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model.

Zhou R, Mazurchuk RV, Tamburlin JH, Harrold JM, Mager DE, Straubinger RM. Zhou R, et al. Among authors: mager de. J Pharmacol Exp Ther. 2010 Feb;332(2):479-88. doi: 10.1124/jpet.109.160044. Epub 2009 Oct 27. J Pharmacol Exp Ther. 2010. PMID: 19861574 Free PMC article.

10

Pharmacokinetic interactions between monoamine oxidase A inhibitor harmaline and 5-methoxy-N,N-dimethyltryptamine, and the impact of CYP2D6 status.

Jiang XL, Shen HW, Mager DE, Yu AM. Jiang XL, et al. Among authors: mager de. Drug Metab Dispos. 2013 May;41(5):975-86. doi: 10.1124/dmd.112.050724. Epub 2013 Feb 7. Drug Metab Dispos. 2013. PMID: 23393220 Free PMC article.

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