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The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
Katayama R, Gong B, Togashi N, Miyamoto M, Kiga M, Iwasaki S, Kamai Y, Tominaga Y, Takeda Y, Kagoshima Y, Shimizu Y, Seto Y, Oh-Hara T, Koike S, Nakao N, Hanzawa H, Watanabe K, Yoda S, Yanagitani N, Hata AN, Shaw AT, Nishio M, Fujita N, Isoyama T. Katayama R, et al. Among authors: shimizu y. Nat Commun. 2019 Aug 9;10(1):3604. doi: 10.1038/s41467-019-11496-z. Nat Commun. 2019. PMID: 31399568 Free PMC article.
U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors.
Papadopoulos KP, Borazanci E, Shaw AT, Katayama R, Shimizu Y, Zhu VW, Sun TY, Wakelee HA, Madison R, Schrock AB, Senaldi G, Nakao N, Hanzawa H, Tachibana M, Isoyama T, Nakamaru K, Deng C, Li M, Fan F, Zhao Q, Gao Y, Seto T, Jänne PA, Ou SI. Papadopoulos KP, et al. Among authors: shimizu y. Clin Cancer Res. 2020 Sep 15;26(18):4785-4794. doi: 10.1158/1078-0432.CCR-20-1630. Epub 2020 Jun 26. Clin Cancer Res. 2020. PMID: 32591465 Clinical Trial.
Dental Suction Interference and Acoustic Respiratory Monitoring.
Tabata E, Shimizu Y, Oue K, Saeki N, Ohshimo S, Mukai A, Ishikawa H, Kamio H, Yoshida M, Shime N. Tabata E, et al. Among authors: shimizu y. Anesth Prog. 2024 Dec 4;71(4):171-175. doi: 10.2344/23-00017. Anesth Prog. 2024. PMID: 39711455
Multiomics analyses reveal adipose-derived stem cells inhibit the inflammatory response of M1-like macrophages through secreting lactate.
Horie T, Hirata H, Sakamoto T, Kitajima H, Fuku A, Nakamura Y, Sunatani Y, Tanida I, Sunami H, Tachi Y, Ishigaki Y, Yamamoto N, Shimizu Y, Ichiseki T, Kaneuji A, Iwabuchi K, Osawa S, Kawahara N. Horie T, et al. Among authors: shimizu y. Stem Cell Res Ther. 2024 Dec 18;15(1):485. doi: 10.1186/s13287-024-04072-w. Stem Cell Res Ther. 2024. PMID: 39696485 Free PMC article.
Validating knowledge-based volumetric modulated arc therapy plans with a multi-institution model (broad model) using a complete open-loop dataset for prostate cancer.
Ito T, Kubo K, Nakahara R, Fukunaga JI, Ueda Y, Kamima T, Shimizu Y, Hirata M, Kawamorita R, Ishii K, Nakamatsu K, Monzen H. Ito T, et al. Among authors: shimizu y. Phys Eng Sci Med. 2024 Dec 18. doi: 10.1007/s13246-024-01505-x. Online ahead of print. Phys Eng Sci Med. 2024. PMID: 39693039
6,165 results