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M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression.
Yadav P, Subbarayalu P, Medina D, Nirzhor S, Timilsina S, Rajamanickam S, Eedunuri VK, Gupta Y, Zheng S, Abdelfattah N, Huang Y, Vadlamudi R, Hromas R, Meltzer P, Houghton P, Chen Y, Rao MK. Yadav P, et al. Among authors: hromas r. Cancer Res. 2022 May 16;82(10):1872-1889. doi: 10.1158/0008-5472.CAN-21-2106. Cancer Res. 2022. PMID: 35303054 Free PMC article.
Structural basis of RNA cap modification by SARS-CoV-2.
Viswanathan T, Arya S, Chan SH, Qi S, Dai N, Misra A, Park JG, Oladunni F, Kovalskyy D, Hromas RA, Martinez-Sobrido L, Gupta YK. Viswanathan T, et al. Nat Commun. 2020 Jul 24;11(1):3718. doi: 10.1038/s41467-020-17496-8. Nat Commun. 2020. PMID: 32709886 Free PMC article.
Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor-Induced Synthetic Lethality.
Kornepati AVR, Boyd JT, Murray CE, Saifetiarova J, de la Peña Avalos B, Rogers CM, Bai H, Padron AS, Liao Y, Ontiveros C, Svatek RS, Hromas R, Li R, Hu Y, Conejo-Garcia JR, Vadlamudi RK, Zhao W, Dray E, Sung P, Curiel TJ. Kornepati AVR, et al. Among authors: hromas r. Cancer Res. 2022 Jun 6;82(11):2156-2170. doi: 10.1158/0008-5472.CAN-21-2076. Cancer Res. 2022. PMID: 35247877 Free PMC article.
Targeting aberrant replication and DNA repair events for treating breast cancers.
Rajamanickam S, Park JH, Subbarayalu P, Timilsina S, Bates K, Yadav P, Nirzhor SSR, Eedunuri V, Mohammad TA, Jung KH, Onyeagucha B, Abdelfattah N, Benevides R, Lee G, Chen Y, Vadlamudi R, Brenner A, Kaklamani V, Jatoi I, Kuhn J, Hromas R, Gupta YK, Kaipparettu BA, Arbiser JL, Rao MK. Rajamanickam S, et al. Among authors: hromas r. Commun Biol. 2022 May 24;5(1):493. doi: 10.1038/s42003-022-03413-w. Commun Biol. 2022. PMID: 35610507 Free PMC article.
EEPD1 promotes repair of oxidatively-stressed replication forks.
Jaiswal AS, Kim HS, Schärer OD, Sharma N, Williamson EA, Srinivasan G, Phillips L, Kong K, Arya S, Misra A, Dutta A, Gupta Y, Walter CA, Burma S, Narayan S, Sung P, Nickoloff JA, Hromas R. Jaiswal AS, et al. Among authors: hromas r. NAR Cancer. 2023 Jan 18;5(1):zcac044. doi: 10.1093/narcan/zcac044. eCollection 2023 Mar. NAR Cancer. 2023. PMID: 36683914 Free PMC article.
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
Jaiswal AS, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, Sadideen DT, Kirby A, Williamson EA, Gupta YK, Olsen SK, Xu M, Loranc E, Mukhopadhyay P, Pertsemlidis A, Bishop AJR, Sung P, Nickoloff JA, Hromas R. Jaiswal AS, et al. Among authors: hromas r. Nucleic Acids Res. 2023 Dec 11;51(22):12224-12241. doi: 10.1093/nar/gkad952. Nucleic Acids Res. 2023. PMID: 37953292 Free PMC article.
Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer.
Berwick M, Satagopan JM, Ben-Porat L, Carlson A, Mah K, Henry R, Diotti R, Milton K, Pujara K, Landers T, Dev Batish S, Morales J, Schindler D, Hanenberg H, Hromas R, Levran O, Auerbach AD. Berwick M, et al. Among authors: hromas r. Cancer Res. 2007 Oct 1;67(19):9591-6. doi: 10.1158/0008-5472.CAN-07-1501. Cancer Res. 2007. PMID: 17909071 Free PMC article.
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Among authors: hromas r. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
215 results