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Olaparib beyond progression compared with platinum chemotherapy after secondary cytoreductive surgery in patients with recurrent ovarian cancer: phase III randomized, open-label MITO 35b study, a project of the MITO-MANGO groups.
Schettino C, Musacchio L, Bartoletti M, Chiodini P, Arenare L, Baldassarre G, Califano D, Capoluongo E, Costi MP, D'Incalci M, Marchini S, Mezzanzanica D, Normanno N, Scala S, Greggi S, Perrone F, Pignata S. Schettino C, et al. Among authors: costi mp. Int J Gynecol Cancer. 2022 Jun 6;32(6):799-803. doi: 10.1136/ijgc-2022-003435. Int J Gynecol Cancer. 2022. PMID: 35318277
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents.
Linciano P, Quotadamo A, Luciani R, Santucci M, Zorn KM, Foil DH, Lane TR, Cordeiro da Silva A, Santarem N, B Moraes C, Freitas-Junior L, Wittig U, Mueller W, Tonelli M, Ferrari S, Venturelli A, Gul S, Kuzikov M, Ellinger B, Reinshagen J, Ekins S, Costi MP. Linciano P, et al. Among authors: costi mp. J Med Chem. 2023 Nov 23;66(22):15230-15255. doi: 10.1021/acs.jmedchem.3c01322. Epub 2023 Nov 3. J Med Chem. 2023. PMID: 37921561 Free PMC article.
Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux.
Pérez-Victoria JM, Cortés-Selva F, Parodi-Talice A, Bavchvarov BI, Pérez-Victoria FJ, Muñoz-Martínez F, Maitrejean M, Costi MP, Barron D, Di Pietro A, Castanys S, Gamarro F. Pérez-Victoria JM, et al. Among authors: costi mp. Antimicrob Agents Chemother. 2006 Sep;50(9):3102-10. doi: 10.1128/AAC.00423-06. Antimicrob Agents Chemother. 2006. PMID: 16940108 Free PMC article.
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents.
Francesconi V, Rizzo M, Pozzi C, Tagliazucchi L, Konchie Simo CU, Saporito G, Landi G, Mangani S, Carbone A, Schenone S, Santarém N, Tavares J, Cordeiro-da-Silva A, Costi MP, Tonelli M. Francesconi V, et al. Among authors: costi mp. ACS Infect Dis. 2024 Aug 9;10(8):2755-2774. doi: 10.1021/acsinfecdis.4c00113. Epub 2024 Jul 2. ACS Infect Dis. 2024. PMID: 38953453
Pharmacokinetics and disposition of miltefosine in healthy mice and hamsters experimentally infected with Leishmania infantum.
Jiménez-Antón MD, García-Calvo E, Gutiérrez C, Escribano MD, Kayali N, Luque-García JL, Olías-Molero AI, Corral MJ, Costi MP, Torrado JJ, Alunda JM. Jiménez-Antón MD, et al. Among authors: costi mp. Eur J Pharm Sci. 2018 Aug 30;121:281-286. doi: 10.1016/j.ejps.2018.06.002. Epub 2018 Jun 5. Eur J Pharm Sci. 2018. PMID: 29883726
Oxaliplatin plus leucovorin and 5-fluorouracil (FOLFOX-4) as a salvage chemotherapy in heavily-pretreated platinum-resistant ovarian cancer.
Conteduca V, Gurioli G, Rossi L, Scarpi E, Lolli C, Schepisi G, Farolfi A, De Lisi D, Gallà V, Burgio SL, Menna C, Amadori A, Losi L, Amadori D, Costi MP, De Giorgi U. Conteduca V, et al. Among authors: costi mp. BMC Cancer. 2018 Dec 19;18(1):1267. doi: 10.1186/s12885-018-5180-1. BMC Cancer. 2018. PMID: 30567527 Free PMC article.
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells.
Marverti G, Gozzi G, Maretti E, Lauriola A, Severi L, Sacchetti F, Losi L, Pacifico S, Ferrari S, Ponterini G, Leo E, Costi MP, D'Arca D. Marverti G, et al. Among authors: costi mp. Int J Mol Sci. 2020 Jun 23;21(12):4452. doi: 10.3390/ijms21124452. Int J Mol Sci. 2020. PMID: 32585842 Free PMC article.
145 results