Chen Y - Search Results

1

CRISPR/Cas9-Based Functional Genomics in Human Induced Pluripotent Stem Cell-Derived Models: Can "the Stars Align" for Neurodegenerative Diseases?

Chen Y, Jong TT, Chen C, Sidransky E. Chen Y, et al. Among authors: chen c. Mov Disord. 2022 May;37(5):886-890. doi: 10.1002/mds.28998. Epub 2022 Mar 26. Mov Disord. 2022. PMID: 35338523 No abstract available.

2

Glucocerebrosidase as a therapeutic target for Parkinson's disease.

Chen Y, Sam R, Sharma P, Chen L, Do J, Sidransky E. Chen Y, et al. Among authors: chen l. Expert Opin Ther Targets. 2020 Apr;24(4):287-294. doi: 10.1080/14728222.2020.1733970. Epub 2020 Feb 27. Expert Opin Ther Targets. 2020. PMID: 32106725 Free PMC article. Review.

3

Lysosomal dysfunction in neurodegeneration: emerging concepts and methods.

Udayar V, Chen Y, Sidransky E, Jagasia R. Udayar V, et al. Among authors: chen y. Trends Neurosci. 2022 Mar;45(3):184-199. doi: 10.1016/j.tins.2021.12.004. Epub 2022 Jan 13. Trends Neurosci. 2022. PMID: 35034773 Free PMC article. Review.

4

Lyso-IP: Uncovering Pathogenic Mechanisms of Lysosomal Dysfunction.

Chen C, Sidransky E, Chen Y. Chen C, et al. Among authors: chen y. Biomolecules. 2022 Apr 21;12(5):616. doi: 10.3390/biom12050616. Biomolecules. 2022. PMID: 35625544 Free PMC article. Review.

5

Technological advances expand our knowledge of lysosomal dysfunction in neurodegeneration.

Chen C, Chen Y, Sidransky E. Chen C, et al. Among authors: chen y. Neural Regen Res. 2023 Mar;18(3):539-540. doi: 10.4103/1673-5374.346490. Neural Regen Res. 2023. PMID: 36018167 Free PMC article. No abstract available.

6

Targeting protein clearance pathways in GBA1-associated Parkinson disease.

Chen C, Hertz E, Chen Y, Sidransky E. Chen C, et al. Among authors: chen y. Expert Opin Ther Targets. 2022 Dec;26(12):1031-1035. doi: 10.1080/14728222.2022.2166828. Epub 2023 Jan 12. Expert Opin Ther Targets. 2022. PMID: 36628605 Free PMC article. No abstract available.

7

Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson Disease Research.

Jong T, Gehrlein A, Sidransky E, Jagasia R, Chen Y. Jong T, et al. Among authors: chen y. bioRxiv [Preprint]. 2023 Sep 15:2023.09.14.557851. doi: 10.1101/2023.09.14.557851. bioRxiv. 2023. Update in: J Parkinsons Dis. 2024;14(1):65-78. doi: 10.3233/JPD-230295 PMID: 37886493 Free PMC article. Updated. Preprint.

8

New tools can propel research in lysosomal storage diseases.

Hertz E, Glasstetter LM, Chen Y, Sidransky E. Hertz E, et al. Among authors: chen y. Mol Genet Metab. 2023 Dec;140(4):107729. doi: 10.1016/j.ymgme.2023.107729. Epub 2023 Nov 3. Mol Genet Metab. 2023. PMID: 37951057

9

Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson's Disease Research.

Jong T, Gehrlein A, Sidransky E, Jagasia R, Chen Y. Jong T, et al. Among authors: chen y. J Parkinsons Dis. 2024;14(1):65-78. doi: 10.3233/JPD-230295. J Parkinsons Dis. 2024. PMID: 38251062 Free PMC article.

10

Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease.

Williams D, Glasstetter LM, Jong TT, Kapoor A, Zhu S, Zhu Y, Gehrlein A, Vocadlo DJ, Jagasia R, Marugan JJ, Sidransky E, Henderson MJ, Chen Y. Williams D, et al. Among authors: chen y. bioRxiv [Preprint]. 2024 Mar 27:2024.03.22.586364. doi: 10.1101/2024.03.22.586364. bioRxiv. 2024. PMID: 38712038 Free PMC article. Preprint.

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