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Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36.5 °C or above.
de Ridder IR, de Jong FJ, den Hertog HM, Lingsma HF, van Gemert HM, Schreuder AH, Ruitenberg A, Maasland EL, Saxena R, Oomes P, van Tuijl J, Koudstaal PJ, Kappelle LJ, Algra A, van der Worp HB, Dippel DW. de Ridder IR, et al. Among authors: den hertog hm. Int J Stroke. 2015 Apr;10(3):457-62. doi: 10.1111/ijs.12053. Epub 2013 May 22. Int J Stroke. 2015. PMID: 23692587 Clinical Trial.
Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke: A Randomized Clinical Trial.
Fransen PS, Berkhemer OA, Lingsma HF, Beumer D, van den Berg LA, Yoo AJ, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJ, van Walderveen MA, Staals J, Hofmeijer J, van Oostayen JA, Lycklama À Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de Vries J, de Kort PL, van den Berg JS, van Hasselt BA, Aerden LA, Dallinga RJ, Visser MC, Bot JC, Vroomen PC, Eshghi O, Schreuder TH, Heijboer RJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Marquering HA, Sprengers ME, Jenniskens SF, Beenen LF, van den Berg R, Koudstaal PJ, van Zwam WH, Roos YB, van Oostenbrugge RJ, Majoie CB, van der Lugt A, Dippel DW; Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands Investigators. Fransen PS, et al. Among authors: den hertog hm. JAMA Neurol. 2016 Feb;73(2):190-6. doi: 10.1001/jamaneurol.2015.3886. JAMA Neurol. 2016. PMID: 26716735 Clinical Trial.
Thrombus Permeability Is Associated With Improved Functional Outcome and Recanalization in Patients With Ischemic Stroke.
Santos EM, Marquering HA, den Blanken MD, Berkhemer OA, Boers AM, Yoo AJ, Beenen LF, Treurniet KM, Wismans C, van Noort K, Lingsma HF, Dippel DW, van der Lugt A, van Zwam WH, Roos YB, van Oostenbrugge RJ, Niessen WJ, Majoie CB; MR CLEAN Investigators. Santos EM, et al. Stroke. 2016 Mar;47(3):732-41. doi: 10.1161/STROKEAHA.115.011187. Epub 2016 Feb 4. Stroke. 2016. PMID: 26846859 Clinical Trial.
Does prior antiplatelet treatment improve functional outcome after intra-arterial treatment for acute ischemic stroke?
Mulder MJ, Berkhemer OA, Fransen PS, van den Berg LA, Lingsma HF, den Hertog HM, Staals J, Jenniskens SF, van Oostenbrugge RJ, van Zwam WH, Majoie CB, van der Lugt A, Dippel DW; MR CLEAN investigators. Mulder MJ, et al. Among authors: den hertog hm. Int J Stroke. 2017 Jun;12(4):368-376. doi: 10.1177/1747493016677842. Epub 2016 Jan 1. Int J Stroke. 2017. PMID: 27807281
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