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Page 1
Mosaic RBD nanoparticles protect against multiple sarbecovirus challenges in animal models.
Cohen AA, van Doremalen N, Greaney AJ, Andersen H, Sharma A, Starr TN, Keeffe JR, Fan C, Schulz JE, Gnanapragasam PNP, Kakutani LM, West AP Jr, Saturday G, Lee YE, Gao H, Jette CA, Lewis MG, Tan TK, Townsend AR, Bloom JD, Munster VJ, Bjorkman PJ. Cohen AA, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2022 Mar 28:2022.03.25.485875. doi: 10.1101/2022.03.25.485875. bioRxiv. 2022. Update in: Science. 2022 Aug 5;377(6606):eabq0839. doi: 10.1126/science.abq0839 PMID: 35378752 Free PMC article. Updated. Preprint.
Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates.
Corbett KS, Nason MC, Flach B, Gagne M, O' Connell S, Johnston TS, Shah SN, Edara VV, Floyd K, Lai L, McDanal C, Francica JR, Flynn B, Wu K, Choi A, Koch M, Abiona OM, Werner AP, Alvarado GS, Andrew SF, Donaldson MM, Fintzi J, Flebbe DR, Lamb E, Noe AT, Nurmukhambetova ST, Provost SJ, Cook A, Dodson A, Faudree A, Greenhouse J, Kar S, Pessaint L, Porto M, Steingrebe K, Valentin D, Zouantcha S, Bock KW, Minai M, Nagata BM, Moliva JI, van de Wetering R, Boyoglu-Barnum S, Leung K, Shi W, Yang ES, Zhang Y, Todd JM, Wang L, Andersen H, Foulds KE, Edwards DK, Mascola JR, Moore IN, Lewis MG, Carfi A, Montefiori D, Suthar MS, McDermott A, Sullivan NJ, Roederer M, Douek DC, Graham BS, Seder RA. Corbett KS, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2021 Apr 23:2021.04.20.440647. doi: 10.1101/2021.04.20.440647. bioRxiv. 2021. Update in: Science. 2021 Sep 17;373(6561):eabj0299. doi: 10.1126/science.abj0299 PMID: 33907752 Free PMC article. Updated. Preprint.
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters.
Wuertz KM, Barkei EK, Chen WH, Martinez EJ, Lakhal-Naouar I, Jagodzinski LL, Paquin-Proulx D, Gromowski GD, Swafford I, Ganesh A, Dong M, Zeng X, Thomas PV, Sankhala RS, Hajduczki A, Peterson CE, Kuklis C, Soman S, Wieczorek L, Zemil M, Anderson A, Darden J, Hernandez H, Grove H, Dussupt V, Hack H, de la Barrera R, Zarling S, Wood JF, Froude JW, Gagne M, Henry AR, Mokhtari EB, Mudvari P, Krebs SJ, Pekosz AS, Currier JR, Kar S, Porto M, Winn A, Radzyminski K, Lewis MG, Vasan S, Suthar M, Polonis VR, Matyas GR, Boritz EA, Douek DC, Seder RA, Daye SP, Rao M, Peel SA, Joyce MG, Bolton DL, Michael NL, Modjarrad K. Wuertz KM, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2021 Jun 16:2021.06.16.448525. doi: 10.1101/2021.06.16.448525. bioRxiv. 2021. Update in: NPJ Vaccines. 2021 Oct 28;6(1):129. doi: 10.1038/s41541-021-00392-7 PMID: 34159328 Free PMC article. Updated. Preprint.
A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates.
Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, Bowman L, Naranjo CA, Yun D, Flinchbaugh Z, Pessaint L, Brown R, Velasco J, Teow E, Cook A, Andersen H, Lewis MG, Camp DL, Silverman JM, Kleanthous H, Joshi SB, Volkin DB, Biswas S, Love JC, Barouch DH. Dalvie NC, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2021 Jul 14:2021.07.13.452251. doi: 10.1101/2021.07.13.452251. bioRxiv. 2021. PMID: 34282417 Free PMC article. Preprint.
Synthetic Multiantigen MVA Vaccine COH04S1 Protects Against SARS-CoV-2 in Syrian Hamsters and Non-Human Primates.
Chiuppesi F, Nguyen VH, Park Y, Contreras H, Karpinski V, Faircloth K, Nguyen J, Kha M, Johnson D, Martinez J, Iniguez A, Zhou Q, Kaltcheva T, Frankel P, Kar S, Sharma A, Andersen H, Lewis MG, Shostak Y, Wussow F, Diamond DJ. Chiuppesi F, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2021 Sep 15:2021.09.15.460487. doi: 10.1101/2021.09.15.460487. bioRxiv. 2021. Update in: NPJ Vaccines. 2022 Jan 21;7(1):7. doi: 10.1038/s41541-022-00436-6 PMID: 34545366 Free PMC article. Updated. Preprint.
Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine.
Li D, Martinez DR, Schäfer A, Chen H, Barr M, Sutherland LL, Lee E, Parks R, Mielke D, Edwards W, Newman A, Bock KW, Minai M, Nagata BM, Gagne M, Douek DC, DeMarco CT, Denny TN, Oguin TH 3rd, Brown A, Rountree W, Wang Y, Mansouri K, Edwards RJ, Ferrari G, Sempowski GD, Eaton A, Tang J, Cain DW, Santra S, Pardi N, Weissman D, Tomai MA, Fox CB, Moore IN, Andersen H, Lewis MG, Golding H, Seder R, Khurana S, Baric RS, Montefiori DC, Saunders KO, Haynes BF. Li D, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2022 Feb 14:2022.01.26.477915. doi: 10.1101/2022.01.26.477915. bioRxiv. 2022. Update in: Nat Commun. 2022 Oct 23;13(1):6309. doi: 10.1038/s41467-022-33985-4 PMID: 35118474 Free PMC article. Updated. Preprint.
Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques.
Chandrashekar A, Yu J, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Anioke T, Barrett J, Chung B, Hachmann NP, Lifton M, Miller J, Powers O, Sciacca M, Sellers D, Siamatu M, Surve N, VanWyk H, Wan H, Wu C, Pessaint L, Valentin D, Van Ry A, Muench J, Boursiquot M, Cook A, Velasco J, Teow E, Boon ACM, Suthar MS, Jain N, Martinot AJ, Lewis MG, Andersen H, Barouch DH. Chandrashekar A, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2022 Feb 7:2022.02.06.479285. doi: 10.1101/2022.02.06.479285. bioRxiv. 2022. Update in: Cell. 2022 Apr 28;185(9):1549-1555.e11. doi: 10.1016/j.cell.2022.03.024 PMID: 35169798 Free PMC article. Updated. Preprint.
RBD-based high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.
Gagne M, Flynn BJ, Honeycutt CC, Flebbe DR, Andrew SF, Provost SJ, McCormick L, Van Ry A, McCarthy E, Todd JM, Bao S, Teng IT, Marciano S, Rudich Y, Li C, Pessaint L, Dodson A, Cook A, Lewis MG, Andersen H, Zahradník J, Nason MC, Foulds KE, Kwong PD, Roederer M, Schreiber G, Seder RA, Douek DC. Gagne M, et al. Among authors: lewis mg. bioRxiv [Preprint]. 2023 Jun 12:2023.06.09.544432. doi: 10.1101/2023.06.09.544432. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 12;15(1):6894. doi: 10.1038/s41467-024-51046-w PMID: 37503026 Free PMC article. Updated. Preprint.
407 results