Xue W - Search Results

1

A split prime editor with untethered reverse transcriptase and circular RNA template.

Liu B, Dong X, Cheng H, Zheng C, Chen Z, Rodríguez TC, Liang SQ, Xue W, Sontheimer EJ. Liu B, et al. Among authors: xue w. Nat Biotechnol. 2022 Sep;40(9):1388-1393. doi: 10.1038/s41587-022-01255-9. Epub 2022 Apr 4. Nat Biotechnol. 2022. PMID: 35379962

2

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

Yin H, Xue W, Chen S, Bogorad RL, Benedetti E, Grompe M, Koteliansky V, Sharp PA, Jacks T, Anderson DG. Yin H, et al. Among authors: xue w. Nat Biotechnol. 2014 Jun;32(6):551-3. doi: 10.1038/nbt.2884. Epub 2014 Mar 30. Nat Biotechnol. 2014. PMID: 24681508 Free PMC article.

3

Rapid modelling of cooperating genetic events in cancer through somatic genome editing.

Sánchez-Rivera FJ, Papagiannakopoulos T, Romero R, Tammela T, Bauer MR, Bhutkar A, Joshi NS, Subbaraj L, Bronson RT, Xue W, Jacks T. Sánchez-Rivera FJ, et al. Among authors: xue w. Nature. 2014 Dec 18;516(7531):428-31. doi: 10.1038/nature13906. Epub 2014 Oct 22. Nature. 2014. PMID: 25337879 Free PMC article.

4

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

Wang D, Mou H, Li S, Li Y, Hough S, Tran K, Li J, Yin H, Anderson DG, Sontheimer EJ, Weng Z, Gao G, Xue W. Wang D, et al. Among authors: xue w. Hum Gene Ther. 2015 Jul;26(7):432-42. doi: 10.1089/hum.2015.087. Hum Gene Ther. 2015. PMID: 26086867 Free PMC article.

5

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.

Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, Weng Z, Dong Y, Koteliansky V, Wolfe SA, Langer R, Xue W, Anderson DG. Yin H, et al. Among authors: xue w. Nat Biotechnol. 2016 Mar;34(3):328-33. doi: 10.1038/nbt.3471. Epub 2016 Feb 1. Nat Biotechnol. 2016. PMID: 26829318 Free PMC article.

6

CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.

Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W. Mou H, et al. Among authors: xue w. Genome Biol. 2017 Jun 14;18(1):108. doi: 10.1186/s13059-017-1237-8. Genome Biol. 2017. PMID: 28615073 Free PMC article.

7

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG. Yin H, et al. Among authors: xue w. Nat Biotechnol. 2017 Dec;35(12):1179-1187. doi: 10.1038/nbt.4005. Epub 2017 Nov 13. Nat Biotechnol. 2017. PMID: 29131148 Free PMC article.

8

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.

Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG. Yin H, et al. Among authors: xue w. Nat Chem Biol. 2018 Mar;14(3):311-316. doi: 10.1038/nchembio.2559. Epub 2018 Jan 29. Nat Chem Biol. 2018. PMID: 29377001 Free PMC article.

9

CRISPR-Cas-related technologies in basic and translational liver research.

Song CQ, Xue W. Song CQ, et al. Among authors: xue w. Nat Rev Gastroenterol Hepatol. 2018 May;15(5):251-252. doi: 10.1038/nrgastro.2018.11. Epub 2018 Feb 14. Nat Rev Gastroenterol Hepatol. 2018. PMID: 29443117 Free PMC article.

10

Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice.

Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G. Wang D, et al. Among authors: xue w. Nat Biotechnol. 2018 Oct;36(9):839-842. doi: 10.1038/nbt.4219. Epub 2018 Aug 13. Nat Biotechnol. 2018. PMID: 30102296 Free PMC article.

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