Levine AJ - Search Results

1

The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein.

Hoyos D, Greenbaum B, Levine AJ. Hoyos D, et al. Among authors: levine aj. Cell Death Differ. 2022 May;29(5):938-945. doi: 10.1038/s41418-022-00980-7. Epub 2022 Apr 5. Cell Death Differ. 2022. PMID: 35383292 Free PMC article. Review.

2

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation.

Momand J, Zambetti GP, Olson DC, George D, Levine AJ. Momand J, et al. Among authors: levine aj. Cell. 1992 Jun 26;69(7):1237-45. doi: 10.1016/0092-8674(92)90644-r. Cell. 1992. PMID: 1535557

3

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes.

Hinds PW, Finlay CA, Quartin RS, Baker SJ, Fearon ER, Vogelstein B, Levine AJ. Hinds PW, et al. Among authors: levine aj. Cell Growth Differ. 1990 Dec;1(12):571-80. Cell Growth Differ. 1990. PMID: 2288874

4

The p53 proto-oncogene can act as a suppressor of transformation.

Finlay CA, Hinds PW, Levine AJ. Finlay CA, et al. Among authors: levine aj. Cell. 1989 Jun 30;57(7):1083-93. doi: 10.1016/0092-8674(89)90045-7. Cell. 1989. PMID: 2525423

5

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

Lu H, Levine AJ. Lu H, et al. Among authors: levine aj. Proc Natl Acad Sci U S A. 1995 May 23;92(11):5154-8. doi: 10.1073/pnas.92.11.5154. Proc Natl Acad Sci U S A. 1995. PMID: 7761466 Free PMC article.

6

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity.

Bayle JH, Elenbaas B, Levine AJ. Bayle JH, et al. Among authors: levine aj. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5729-33. doi: 10.1073/pnas.92.12.5729. Proc Natl Acad Sci U S A. 1995. PMID: 7777576 Free PMC article.

7

Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants.

Lin J, Teresky AK, Levine AJ. Lin J, et al. Among authors: levine aj. Oncogene. 1995 Jun 15;10(12):2387-90. Oncogene. 1995. PMID: 7784087

8

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.

Lin J, Chen J, Elenbaas B, Levine AJ. Lin J, et al. Among authors: levine aj. Genes Dev. 1994 May 15;8(10):1235-46. doi: 10.1101/gad.8.10.1235. Genes Dev. 1994. PMID: 7926727 Free article.

9

Gain of function mutations in p53.

Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ. Dittmer D, et al. Among authors: levine aj. Nat Genet. 1993 May;4(1):42-6. doi: 10.1038/ng0593-42. Nat Genet. 1993. PMID: 8099841

10

The properties of p53 proteins selected for the loss of suppression of transformation.

Olson DC, Levine AJ. Olson DC, et al. Among authors: levine aj. Cell Growth Differ. 1994 Jan;5(1):61-71. Cell Growth Differ. 1994. PMID: 8123594

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