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A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
Rodrigues E, Jung J, Park H, Loo C, Soukhtehzari S, Kitova EN, Mozaneh F, Daskhan G, Schmidt EN, Aghanya V, Sarkar S, Streith L, St Laurent CD, Nguyen L, Julien JP, West LJ, Williams KC, Klassen JS, Macauley MS. Rodrigues E, et al. Among authors: macauley ms. Nat Commun. 2020 Oct 9;11(1):5091. doi: 10.1038/s41467-020-18907-6. Nat Commun. 2020. PMID: 33037195 Free PMC article.
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Nguyen L, McCord KA, Bui DT, Bouwman KM, Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, Lowary TL, West LJ, Hsu SD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS, Klassen JS. Nguyen L, et al. Among authors: macauley ms. Nat Chem Biol. 2022 Jan;18(1):81-90. doi: 10.1038/s41589-021-00924-1. Epub 2021 Nov 9. Nat Chem Biol. 2022. PMID: 34754101
Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.
Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Among authors: macauley ms. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.
Flow Cytometry-Based Detection of Siglec Ligands.
Schmidt EN, Jung J, Macauley MS. Schmidt EN, et al. Among authors: macauley ms. Methods Mol Biol. 2023;2657:181-193. doi: 10.1007/978-1-0716-3151-5_13. Methods Mol Biol. 2023. PMID: 37149531
Absolute Affinities from Quantitative Shotgun Glycomics Using Concentration-Independent (COIN) Native Mass Spectrometry.
Bui DT, Favell J, Kitova EN, Li Z, McCord KA, Schmidt EN, Mozaneh F, Elaish M, El-Hawiet A, St-Pierre Y, Hobman TC, Macauley MS, Mahal LK, Flynn MR, Klassen JS. Bui DT, et al. Among authors: macauley ms. ACS Cent Sci. 2023 Jun 15;9(7):1374-1387. doi: 10.1021/acscentsci.3c00294. eCollection 2023 Jul 26. ACS Cent Sci. 2023. PMID: 37521792 Free PMC article.
112 results