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Page 1
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications.
Ottanà R, Maccari R, Giglio M, Del Corso A, Cappiello M, Mura U, Cosconati S, Marinelli L, Novellino E, Sartini S, La Motta C, Da Settimo F. Ottanà R, et al. Among authors: cosconati s. Eur J Med Chem. 2011 Jul;46(7):2797-806. doi: 10.1016/j.ejmech.2011.03.068. Epub 2011 Apr 8. Eur J Med Chem. 2011. PMID: 21531055
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75.
Cuzzucoli Crucitti G, Pescatori L, Messore A, Madia VN, Pupo G, Saccoliti F, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Novellino E, Debyser Z, Christ F, Costi R, Di Santo R. Cuzzucoli Crucitti G, et al. Among authors: cosconati s. Eur J Med Chem. 2015 Aug 28;101:288-94. doi: 10.1016/j.ejmech.2015.06.036. Epub 2015 Jun 22. Eur J Med Chem. 2015. PMID: 26150289
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides.
Barresi E, Bruno A, Taliani S, Cosconati S, Da Pozzo E, Salerno S, Simorini F, Daniele S, Giacomelli C, Marini AM, La Motta C, Marinelli L, Cosimelli B, Novellino E, Greco G, Da Settimo F, Martini C. Barresi E, et al. Among authors: cosconati s. J Med Chem. 2015 Aug 13;58(15):6081-92. doi: 10.1021/acs.jmedchem.5b00689. Epub 2015 Jul 28. J Med Chem. 2015. PMID: 26177193
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2.
Salerno S, Marini AM, Fornaciari G, Simorini F, La Motta C, Taliani S, Sartini S, Da Settimo F, García-Argáez AN, Gia O, Cosconati S, Novellino E, D'Ocon P, Fioravanti A, Orlandi P, Bocci G, Dalla Via L. Salerno S, et al. Among authors: cosconati s. Eur J Med Chem. 2015 Oct 20;103:29-43. doi: 10.1016/j.ejmech.2015.08.027. Epub 2015 Aug 14. Eur J Med Chem. 2015. PMID: 26318056
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.
Eadsforth TC, Pinto A, Luciani R, Tamborini L, Cullia G, De Micheli C, Marinelli L, Cosconati S, Novellino E, Lo Presti L, Cordeiro da Silva A, Conti P, Hunter WN, Costi MP. Eadsforth TC, et al. Among authors: cosconati s. J Med Chem. 2015 Oct 22;58(20):7938-48. doi: 10.1021/acs.jmedchem.5b00687. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26322631 Free PMC article.
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas.
Daniele S, La Pietra V, Barresi E, Di Maro S, Da Pozzo E, Robello M, La Motta C, Cosconati S, Taliani S, Marinelli L, Novellino E, Martini C, Da Settimo F. Daniele S, et al. Among authors: cosconati s. J Med Chem. 2016 May 26;59(10):4526-38. doi: 10.1021/acs.jmedchem.5b01767. Epub 2016 May 3. J Med Chem. 2016. PMID: 27050782
135 results