Melin J - Search Results

1

Dapagliflozin Pharmacokinetics Is Similar in Adults With Type 1 and Type 2 Diabetes Mellitus.

Melin J, Tang W, Rekić D, Hamrén B, Penland RC, Boulton DW, Parkinson J. Melin J, et al. J Clin Pharmacol. 2022 Oct;62(10):1227-1235. doi: 10.1002/jcph.2062. Epub 2022 May 2. J Clin Pharmacol. 2022. PMID: 35403243 Free PMC article.

2

Model-based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus.

Parkinson J, Tang W, Åstrand M, Melin J, Ekholm E, Hamrén B, Boulton DW. Parkinson J, et al. Among authors: melin j. Diabetes Obes Metab. 2019 Jun;21(6):1381-1387. doi: 10.1111/dom.13664. Epub 2019 Mar 14. Diabetes Obes Metab. 2019. PMID: 30756462 Free PMC article. Clinical Trial.

3

Evaluation of the Pharmacokinetics of Dapagliflozin in Patients With Chronic Kidney Disease With or Without Type 2 Diabetes Mellitus.

Penland RC, Melin J, Boulton DW, Tang W. Penland RC, et al. Among authors: melin j. J Clin Pharmacol. 2023 May;63(5):551-559. doi: 10.1002/jcph.2196. Epub 2023 Jan 12. J Clin Pharmacol. 2023. PMID: 36543754

4

Dapagliflozin pharmacokinetics is similar between patients with heart failure with reduced ejection fraction and patients with type 2 diabetes mellitus.

Melin J, Parkinson J, Hamrén B, Penland RC, Boulton DW, Tang W. Melin J, et al. Br J Clin Pharmacol. 2024 Feb;90(2):606-612. doi: 10.1111/bcp.15939. Epub 2023 Nov 20. Br J Clin Pharmacol. 2024. PMID: 37897064

5

Concentration-QT modeling demonstrates that the selective mineralocorticoid receptor modulator, balcinrenone (AZD9977), does not prolong QT interval.

Sundell J, Rekic D, Melin J, Johansson S, Ebrahimi A, Dota C, Parkinson J. Sundell J, et al. Among authors: melin j. CPT Pharmacometrics Syst Pharmacol. 2024 Nov 5. doi: 10.1002/psp4.13272. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39497618 Free article.

6

Pharmacokinetics of the Inhaled Selective Glucocorticoid Receptor Modulator AZD5423 Following Inhalation Using Different Devices.

Melin J, Prothon S, Kloft C, Cleton A, Amilon C, Jorup C, Bäckman P, Olsson B, Hamrén UW. Melin J, et al. AAPS J. 2017 May;19(3):865-874. doi: 10.1208/s12248-016-0042-8. Epub 2017 Mar 9. AAPS J. 2017. PMID: 28281196 Clinical Trial.

7

Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial.

Squire IB, Gabrielsen A, Greasley PJ, Wernevik L, Hartleib-Geschwindner J, Holden J, Johansson S, Rudvik A, Sánchez J, Bamberg K, Melin J, Whittaker A. Squire IB, et al. Among authors: melin j. Clin Transl Sci. 2022 Oct;15(10):2493-2504. doi: 10.1111/cts.13377. Epub 2022 Aug 20. Clin Transl Sci. 2022. PMID: 35971596 Free PMC article. Clinical Trial.

8

Pharmacokinetics and pharmacokinetic-pharmacodynamic relationships of monoclonal antibodies in children.

Edlund H, Melin J, Parra-Guillen ZP, Kloft C. Edlund H, et al. Among authors: melin j. Clin Pharmacokinet. 2015 Jan;54(1):35-80. doi: 10.1007/s40262-014-0208-4. Clin Pharmacokinet. 2015. PMID: 25516414 Review.

9

The circadian rhythm of corticosteroid-binding globulin has little impact on cortisol exposure after hydrocortisone dosing.

Melin J, Hartung N, Parra-Guillen ZP, Whitaker MJ, Ross RJ, Kloft C. Melin J, et al. Clin Endocrinol (Oxf). 2019 Jul;91(1):33-40. doi: 10.1111/cen.13969. Epub 2019 Apr 9. Clin Endocrinol (Oxf). 2019. PMID: 30868607 Free article. Clinical Trial.

10

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach.

Michelet R, Bindellini D, Melin J, Neumann U, Blankenstein O, Huisinga W, Johnson TN, Whitaker MJ, Ross R, Kloft C. Michelet R, et al. Among authors: melin j. Front Pharmacol. 2023 Jan 12;13:1090554. doi: 10.3389/fphar.2022.1090554. eCollection 2022. Front Pharmacol. 2023. PMID: 36712688 Free PMC article.

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