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The grapefruit polyphenol naringenin inhibits multiple cardiac ion channels.
Sanson C, Boukaiba R, Houtmann S, Maizières MA, Fouconnier S, Partiseti M, Bohme GA. Sanson C, et al. Among authors: bohme ga. Naunyn Schmiedebergs Arch Pharmacol. 2022 Jun;395(6):735-740. doi: 10.1007/s00210-022-02240-4. Epub 2022 Apr 12. Naunyn Schmiedebergs Arch Pharmacol. 2022. PMID: 35412073
In vitro ion channel profile and ex vivo cardiac electrophysiology properties of the R(-) and S(+) enantiomers of hydroxychloroquine.
Ballet V, Bohme GA, Brohan E, Boukaiba R, Chambard JM, Angouillant-Boniface O, Carriot T, Chantoiseau C, Fouconnier S, Houtmann S, Prévost C, Schombert B, Schio L, Partiseti M. Ballet V, et al. Among authors: bohme ga. Eur J Pharmacol. 2022 Jan 15;915:174670. doi: 10.1016/j.ejphar.2021.174670. Epub 2021 Dec 2. Eur J Pharmacol. 2022. PMID: 34863995 Free PMC article.
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Kramer J, et al. Among authors: bohme ga. Sci Rep. 2020 Mar 27;10(1):5627. doi: 10.1038/s41598-020-62344-w. Sci Rep. 2020. PMID: 32221320 Free PMC article.
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
Canton T, Böhme GA, Boireau A, Bordier F, Mignani S, Jimonet P, Jahn G, Alavijeh M, Stygall J, Roberts S, Brealey C, Vuilhorgne M, Debono MW, Le Guern S, Laville M, Briet D, Roux M, Stutzmann JM, Pratt J. Canton T, et al. Among authors: bohme ga. J Pharmacol Exp Ther. 2001 Oct;299(1):314-22. J Pharmacol Exp Ther. 2001. PMID: 11561094
Enhancement of memory in cannabinoid CB1 receptor knock-out mice.
Reibaud M, Obinu MC, Ledent C, Parmentier M, Böhme GA, Imperato A. Reibaud M, et al. Among authors: bohme ga. Eur J Pharmacol. 1999 Aug 20;379(1):R1-2. doi: 10.1016/s0014-2999(99)00496-3. Eur J Pharmacol. 1999. PMID: 10499380
61 results