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PEN2: Metformin's new partner at lysosome.
Sakamoto K, Jessen N. Sakamoto K, et al. Cell Res. 2022 Jun;32(6):507-508. doi: 10.1038/s41422-022-00661-7. Cell Res. 2022. PMID: 35418220 Free PMC article. No abstract available.
LKB1 regulates lipid oxidation during exercise independently of AMPK.
Jeppesen J, Maarbjerg SJ, Jordy AB, Fritzen AM, Pehmøller C, Sylow L, Serup AK, Jessen N, Thorsen K, Prats C, Qvortrup K, Dyck JR, Hunter RW, Sakamoto K, Thomson DM, Schjerling P, Wojtaszewski JF, Richter EA, Kiens B. Jeppesen J, et al. Among authors: sakamoto k. Diabetes. 2013 May;62(5):1490-9. doi: 10.2337/db12-1160. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349504 Free PMC article.
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.
Rhein P, Desjardins EM, Rong P, Ahwazi D, Bonhoure N, Stolte J, Santos MD, Ovens AJ, Ehrlich AM, Sanchez Garcia JL, Ouyang Q, Yabut JM, Kjolby M, Membrez M, Jessen N, Oakhill JS, Treebak JT, Maire P, Scott JW, Sanders MJ, Descombes P, Chen S, Steinberg GR, Sakamoto K. Rhein P, et al. Among authors: sakamoto k. Mol Metab. 2021 Sep;51:101228. doi: 10.1016/j.molmet.2021.101228. Epub 2021 Mar 30. Mol Metab. 2021. PMID: 33798773 Free PMC article.
Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.
Neopane K, Kozlov N, Negoita F, Murray-Segal L, Brink R, Hoque A, Ovens AJ, Tjin G, McAloon LM, Yu D, Ling NXY, Sanders MJ, Oakhill JS, Scott JW, Steinberg GR, Loh K, Kemp BE, Sakamoto K, Galic S. Neopane K, et al. Among authors: sakamoto k. Cell Rep. 2022 Dec 20;41(12):111862. doi: 10.1016/j.celrep.2022.111862. Cell Rep. 2022. PMID: 36543129 Free article.
Molecular mechanism of action of metformin: old or new insights?
Rena G, Pearson ER, Sakamoto K. Rena G, et al. Among authors: sakamoto k. Diabetologia. 2013 Sep;56(9):1898-906. doi: 10.1007/s00125-013-2991-0. Epub 2013 Jul 9. Diabetologia. 2013. PMID: 23835523 Free PMC article. Review.
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.
Mottillo EP, Desjardins EM, Crane JD, Smith BK, Green AE, Ducommun S, Henriksen TI, Rebalka IA, Razi A, Sakamoto K, Scheele C, Kemp BE, Hawke TJ, Ortega J, Granneman JG, Steinberg GR. Mottillo EP, et al. Among authors: sakamoto k. Cell Metab. 2016 Jul 12;24(1):118-29. doi: 10.1016/j.cmet.2016.06.006. Cell Metab. 2016. PMID: 27411013 Free PMC article.
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status.
Cameron AR, Morrison VL, Levin D, Mohan M, Forteath C, Beall C, McNeilly AD, Balfour DJ, Savinko T, Wong AK, Viollet B, Sakamoto K, Fagerholm SC, Foretz M, Lang CC, Rena G. Cameron AR, et al. Among authors: sakamoto k. Circ Res. 2016 Aug 19;119(5):652-65. doi: 10.1161/CIRCRESAHA.116.308445. Epub 2016 Jul 14. Circ Res. 2016. PMID: 27418629 Free PMC article. Clinical Trial.
Cellular responses to the metal-binding properties of metformin.
Logie L, Harthill J, Patel K, Bacon S, Hamilton DL, Macrae K, McDougall G, Wang HH, Xue L, Jiang H, Sakamoto K, Prescott AR, Rena G. Logie L, et al. Among authors: sakamoto k. Diabetes. 2012 Jun;61(6):1423-33. doi: 10.2337/db11-0961. Epub 2012 Apr 9. Diabetes. 2012. PMID: 22492524 Free PMC article.
4,911 results