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71 results

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Page 1
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S. Golbourn BJ, et al. Among authors: kohanbash g. Nat Cancer. 2022 May;3(5):629-648. doi: 10.1038/s43018-022-00348-3. Epub 2022 Apr 14. Nat Cancer. 2022. PMID: 35422502 Free PMC article.
CD200 depletion in glioma enhances antitumor immunity and induces tumor rejection.
Raphael I, Mujeeb AA, Ampudia-Mesias E, Sever RE, McClellan B, Frederico SC, Sneiderman CT, Mirji A, Daba A, Puerta-Martinez F, Nisnboym M, Edwards WB, Graner M, Moertel CL, Castro MG, Kohanbash G, Olin MR. Raphael I, et al. Among authors: kohanbash g. bioRxiv [Preprint]. 2024 Sep 10:2024.09.08.611922. doi: 10.1101/2024.09.08.611922. bioRxiv. 2024. PMID: 39314283 Free PMC article. Preprint.
A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets.
Jha RM, Rajasundaram D, Sneiderman C, Schlegel BT, O'Brien C, Xiong Z, Janesko-Feldman K, Trivedi R, Vagni V, Zusman BE, Catapano JS, Eberle A, Desai SM, Jadhav AP, Mihaljevic S, Miller M, Raikwar S, Rani A, Rulney J, Shahjouie S, Raphael I, Kumar A, Phuah CL, Winkler EA, Simon DW, Kochanek PM, Kohanbash G. Jha RM, et al. Among authors: kohanbash g. Neuron. 2024 Sep 25;112(18):3069-3088.e4. doi: 10.1016/j.neuron.2024.06.021. Epub 2024 Jul 16. Neuron. 2024. PMID: 39019041 Free article.
MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression.
Azambuja JH, Yerneni SS, Maurer LM, Crentsil HE, Debom GN, Klei L, Smyers M, Sneiderman CT, Schwab KE, Acharya R, Wu YL, Ekambaram P, Hu D, Gough PJ, Bertin J, Melnick A, Kohanbash G, Bao R, Lucas PC, McAllister-Lucas LM. Azambuja JH, et al. Among authors: kohanbash g. bioRxiv [Preprint]. 2024 Sep 27:2024.09.26.614808. doi: 10.1101/2024.09.26.614808. bioRxiv. 2024. PMID: 39386586 Free PMC article. Preprint.
Glioblastoma vaccines: past, present, and opportunities.
Xiong Z, Raphael I, Olin M, Okada H, Li X, Kohanbash G. Xiong Z, et al. Among authors: kohanbash g. EBioMedicine. 2024 Feb;100:104963. doi: 10.1016/j.ebiom.2023.104963. Epub 2024 Jan 5. EBioMedicine. 2024. PMID: 38183840 Free PMC article. Review.
Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma.
Okada H, Kalinski P, Ueda R, Hoji A, Kohanbash G, Donegan TE, Mintz AH, Engh JA, Bartlett DL, Brown CK, Zeh H, Holtzman MP, Reinhart TA, Whiteside TL, Butterfield LH, Hamilton RL, Potter DM, Pollack IF, Salazar AM, Lieberman FS. Okada H, et al. Among authors: kohanbash g. J Clin Oncol. 2011 Jan 20;29(3):330-6. doi: 10.1200/JCO.2010.30.7744. Epub 2010 Dec 13. J Clin Oncol. 2011. PMID: 21149657 Free PMC article. Clinical Trial.
Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC.
Okada H, Butterfield LH, Hamilton RL, Hoji A, Sakaki M, Ahn BJ, Kohanbash G, Drappatz J, Engh J, Amankulor N, Lively MO, Chan MD, Salazar AM, Shaw EG, Potter DM, Lieberman FS. Okada H, et al. Among authors: kohanbash g. Clin Cancer Res. 2015 Jan 15;21(2):286-94. doi: 10.1158/1078-0432.CCR-14-1790. Epub 2014 Nov 25. Clin Cancer Res. 2015. PMID: 25424847 Free PMC article. Clinical Trial.
71 results