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Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke.
Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J. Bitar L, et al. Among authors: koirala n. Sci Transl Med. 2022 Apr 20;14(641):eabk0135. doi: 10.1126/scitranslmed.abk0135. Epub 2022 Apr 20. Sci Transl Med. 2022. PMID: 35442704
Increased cerebrospinal fluid albumin and immunoglobulin A fractions forecast cortical atrophy and longitudinal functional deterioration in relapsing-remitting multiple sclerosis.
Kroth J, Ciolac D, Fleischer V, Koirala N, Krämer J, Muthuraman M, Luessi F, Bittner S, Gonzalez-Escamilla G, Zipp F, Meuth SG, Groppa S. Kroth J, et al. Among authors: koirala n. Mult Scler. 2019 Mar;25(3):338-343. doi: 10.1177/1352458517748474. Epub 2017 Dec 11. Mult Scler. 2019. PMID: 29226779
124 results