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509 results

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Page 1
Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke.
Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J. Bitar L, et al. Among authors: nitsch r. Sci Transl Med. 2022 Apr 20;14(641):eabk0135. doi: 10.1126/scitranslmed.abk0135. Epub 2022 Apr 20. Sci Transl Med. 2022. PMID: 35442704
Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders.
Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, Röper J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R, Vogt J. Thalman C, et al. Among authors: nitsch r. Mol Psychiatry. 2018 Aug;23(8):1699-1710. doi: 10.1038/s41380-018-0053-1. Epub 2018 May 9. Mol Psychiatry. 2018. PMID: 29743582 Free PMC article.
AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids.
Endle H, Horta G, Stutz B, Muthuraman M, Tegeder I, Schreiber Y, Snodgrass IF, Gurke R, Liu ZW, Sestan-Pesa M, Radyushkin K, Streu N, Fan W, Baumgart J, Li Y, Kloss F, Groppa S, Opel N, Dannlowski U, Grabe HJ, Zipp F, Rácz B, Horvath TL, Nitsch R, Vogt J. Endle H, et al. Among authors: nitsch r. Nat Metab. 2022 Jun;4(6):683-692. doi: 10.1038/s42255-022-00589-7. Epub 2022 Jun 27. Nat Metab. 2022. PMID: 35760867 Free PMC article.
Growth-Promoting Treatment Screening for Corticospinal Neurons in Mouse and Man.
Hanuscheck N, Schnatz A, Thalman C, Lerch S, Gärtner Y, Domingues M, Bitar L, Nitsch R, Zipp F, Vogelaar CF. Hanuscheck N, et al. Among authors: nitsch r. Cell Mol Neurobiol. 2020 Nov;40(8):1327-1338. doi: 10.1007/s10571-020-00820-7. Epub 2020 Mar 14. Cell Mol Neurobiol. 2020. PMID: 32172457 Free PMC article.
Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP.
Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, Tüscher O, Binder H, Ferreiros N, Tegeder I, Morris AJ, Gropa S, Nürnberg P, Toliat MR, Winterer G, Luhmann HJ, Huai J, Nitsch R. Vogt J, et al. Among authors: nitsch r. EMBO Mol Med. 2016 Jan 1;8(1):25-38. doi: 10.15252/emmm.201505677. EMBO Mol Med. 2016. PMID: 26671989 Free PMC article.
Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2.
Fischer C, Endle H, Schumann L, Wilken-Schmitz A, Kaiser J, Gerber S, Vogelaar CF, Schmidt MHH, Nitsch R, Snodgrass I, Thomas D, Vogt J, Tegeder I. Fischer C, et al. Among authors: nitsch r. Cell Mol Life Sci. 2021 Feb;78(3):1029-1050. doi: 10.1007/s00018-020-03553-4. Epub 2020 May 28. Cell Mol Life Sci. 2021. PMID: 32468095 Free PMC article.
Multiple sclerosis - candidate mechanisms underlying CNS atrophy.
Siffrin V, Vogt J, Radbruch H, Nitsch R, Zipp F. Siffrin V, et al. Among authors: nitsch r. Trends Neurosci. 2010 Apr;33(4):202-10. doi: 10.1016/j.tins.2010.01.002. Epub 2010 Feb 12. Trends Neurosci. 2010. PMID: 20153532 Review.
PRG-1 Regulates Synaptic Plasticity via Intracellular PP2A/β1-Integrin Signaling.
Liu X, Huai J, Endle H, Schlüter L, Fan W, Li Y, Richers S, Yurugi H, Rajalingam K, Ji H, Cheng H, Rister B, Horta G, Baumgart J, Berger H, Laube G, Schmitt U, Schmeisser MJ, Boeckers TM, Tenzer S, Vlachos A, Deller T, Nitsch R, Vogt J. Liu X, et al. Among authors: nitsch r. Dev Cell. 2016 Aug 8;38(3):275-90. doi: 10.1016/j.devcel.2016.06.019. Epub 2016 Jul 21. Dev Cell. 2016. PMID: 27453502 Free article.
Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.
Cheng J, Sahani S, Hausrat TJ, Yang JW, Ji H, Schmarowski N, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Maric HM, Hoerder-Suabedissen A, Molnár Z, Prouvot PH, Trimbuch T, Ninnemann O, Huai J, Fan W, Visentin B, Sabbadini R, Strømgaard K, Stroh A, Luhmann HJ, Kneussel M, Nitsch R, Vogt J. Cheng J, et al. Among authors: nitsch r. Neuron. 2016 Oct 5;92(1):126-142. doi: 10.1016/j.neuron.2016.08.035. Epub 2016 Sep 15. Neuron. 2016. PMID: 27641493 Free PMC article.
509 results