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Page 1
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.
Du W, Hurdiss DL, Drabek D, Mykytyn AZ, Kaiser FK, González-Hernández M, Muñoz-Santos D, Lamers MM, van Haperen R, Li W, Drulyte I, Wang C, Sola I, Armando F, Beythien G, Ciurkiewicz M, Baumgärtner W, Guilfoyle K, Smits T, van der Lee J, van Kuppeveld FJM, van Amerongen G, Haagmans BL, Enjuanes L, Osterhaus ADME, Grosveld F, Bosch BJ. Du W, et al. Among authors: munoz santos d. Sci Immunol. 2022 Jul 29;7(73):eabp9312. doi: 10.1126/sciimmunol.abp9312. Epub 2022 Jul 29. Sci Immunol. 2022. PMID: 35471062 Free PMC article.
Nature of viruses and pandemics: Coronaviruses.
Enjuanes L, Sola I, Zúñiga S, Honrubia JM, Bello-Pérez M, Sanz-Bravo A, González-Miranda E, Hurtado-Tamayo J, Requena-Platek R, Wang L, Muñoz-Santos D, Sánchez CM, Esteban A, Ripoll-Gómez J. Enjuanes L, et al. Among authors: munoz santos d. Curr Res Immunol. 2022;3:151-158. doi: 10.1016/j.crimmu.2022.08.003. Epub 2022 Aug 8. Curr Res Immunol. 2022. PMID: 35966177 Free PMC article. Review.
Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor.
González-Rico FJ, Vicente-García C, Fernández A, Muñoz-Santos D, Montoliu L, Morales-Hernández A, Merino JM, Román AC, Fernández-Salguero PM. González-Rico FJ, et al. Among authors: munoz santos d. Epigenetics Chromatin. 2020 Mar 14;13(1):15. doi: 10.1186/s13072-020-00336-w. Epigenetics Chromatin. 2020. PMID: 32169107 Free PMC article.
Interaction between SARS-CoV PBM and Cellular PDZ Domains Leading to Virus Virulence.
Honrubia JM, Valverde JR, Muñoz-Santos D, Ripoll-Gómez J, de la Blanca N, Izquierdo J, Villarejo-Torres M, Marchena-Pasero A, Rueda-Huélamo M, Nombela I, Ruiz-Yuste M, Zuñiga S, Sola I, Enjuanes L. Honrubia JM, et al. Among authors: munoz santos d. Viruses. 2024 Jul 29;16(8):1214. doi: 10.3390/v16081214. Viruses. 2024. PMID: 39205188 Free PMC article.
Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis.
Wang L, Guzman M, Muñoz-Santos D, Honrubia JM, Ripoll-Gomez J, Delgado R, Sola I, Enjuanes L, Zuñiga S. Wang L, et al. Among authors: munoz santos d. Front Cell Infect Microbiol. 2023 Oct 24;13:1268227. doi: 10.3389/fcimb.2023.1268227. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37942479 Free PMC article.
SARS-CoV-2 ORF8 accessory protein is a virulence factor.
Bello-Perez M, Hurtado-Tamayo J, Mykytyn AZ, Lamers MM, Requena-Platek R, Schipper D, Muñoz-Santos D, Ripoll-Gómez J, Esteban A, Sánchez-Cordón PJ, Enjuanes L, Haagmans BL, Sola I. Bello-Perez M, et al. Among authors: munoz santos d. mBio. 2023 Oct 31;14(5):e0045123. doi: 10.1128/mbio.00451-23. Epub 2023 Aug 25. mBio. 2023. PMID: 37623322 Free PMC article.
SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators.
Honrubia JM, Gutierrez-Álvarez J, Sanz-Bravo A, González-Miranda E, Muñoz-Santos D, Castaño-Rodriguez C, Wang L, Villarejo-Torres M, Ripoll-Gómez J, Esteban A, Fernandez-Delgado R, Sánchez-Cordón PJ, Oliveros JC, Perlman S, McCray PB Jr, Sola I, Enjuanes L. Honrubia JM, et al. Among authors: munoz santos d. mBio. 2023 Feb 28;14(1):e0313622. doi: 10.1128/mbio.03136-22. Epub 2023 Jan 10. mBio. 2023. PMID: 36625656 Free PMC article.