McDonnell TCR - Search Results

1

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits Thrombosis in a Chronic Mouse Model of the Antiphospholipid Syndrome.

Willis R, McDonnell TCR, Pericleous C, Gonzalez EB, Schleh A, Romay-Penabad Z, Giles IP, Rahman A. Willis R, et al. Among authors: mcdonnell tcr. Front Immunol. 2022 Apr 11;13:842923. doi: 10.3389/fimmu.2022.842923. eCollection 2022. Front Immunol. 2022. PMID: 35479096 Free PMC article.

2

PEGylated drugs in rheumatology--why develop them and do they work?

McDonnell T, Ioannou Y, Rahman A. McDonnell T, et al. Rheumatology (Oxford). 2014 Mar;53(3):391-6. doi: 10.1093/rheumatology/ket278. Epub 2013 Aug 20. Rheumatology (Oxford). 2014. PMID: 23962623 Free PMC article. Review.

3

Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS.

McDonnell T, Pericleous C, Laurine E, Tommasi R, Garza-Garcia A, Giles I, Ioannou Y, Rahman A. McDonnell T, et al. BMC Biotechnol. 2015 Nov 14;15:104. doi: 10.1186/s12896-015-0222-0. BMC Biotechnol. 2015. PMID: 26576675 Free PMC article.

4

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome.

Pericleous C, Ferreira I, Borghi O, Pregnolato F, McDonnell T, Garza-Garcia A, Driscoll P, Pierangeli S, Isenberg D, Ioannou Y, Giles I, Meroni PL, Rahman A. Pericleous C, et al. PLoS One. 2016 Jun 2;11(6):e0156407. doi: 10.1371/journal.pone.0156407. eCollection 2016. PLoS One. 2016. PMID: 27253369 Free PMC article.

5

Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK.

Bourke LT, McDonnell T, McCormick J, Pericleous C, Ripoll VM, Giles I, Rahman A, Stephanou A, Ioannou Y. Bourke LT, et al. Cell Death Dis. 2017 Jan 12;8(1):e2549. doi: 10.1038/cddis.2016.235. Cell Death Dis. 2017. PMID: 28079888 Free PMC article.

6

Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome.

Artim-Esen B, Smoktunowicz N, McDonnell T, Ripoll VM, Pericleous C, Mackie I, Robinson E, Isenberg D, Rahman A, Ioannou Y, Chambers RC, Giles I. Artim-Esen B, et al. Sci Rep. 2017 Sep 7;7(1):10788. doi: 10.1038/s41598-017-11315-9. Sci Rep. 2017. PMID: 28883515 Free PMC article.

7

Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome.

Ripoll VM, Pregnolato F, Mazza S, Bodio C, Grossi C, McDonnell T, Pericleous C, Meroni PL, Isenberg DA, Rahman A, Giles IP. Ripoll VM, et al. J Autoimmun. 2018 Sep;93:114-123. doi: 10.1016/j.jaut.2018.07.002. Epub 2018 Jul 19. J Autoimmun. 2018. PMID: 30033000 Free PMC article.

8

Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I.

McDonnell T, Artim-Esen B, Wincup C, Ripoll VM, Isenberg D, Giles IP, Rahman A, Pericleous C. McDonnell T, et al. Front Immunol. 2018 Sep 28;9:2244. doi: 10.3389/fimmu.2018.02244. eCollection 2018. Front Immunol. 2018. PMID: 30323817 Free PMC article.

9

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.

McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. McDonnell TCR, et al. Front Immunol. 2018 Oct 22;9:2413. doi: 10.3389/fimmu.2018.02413. eCollection 2018. Front Immunol. 2018. PMID: 30405613 Free PMC article.

10

Domain I of β2GPI is capable of blocking serum IgA antiphospholipid antibodies binding in vitro: an effect enhanced by PEGylation.

Albay A, Artim-Esen B, Pericleous C, Wincup C, Giles I, Rahman A, McDonnell T. Albay A, et al. Lupus. 2019 Jun;28(7):893-897. doi: 10.1177/0961203319851571. Epub 2019 May 24. Lupus. 2019. PMID: 31126213 Free PMC article.

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