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Multivalent interactions essential for lentiviral integrase function.
Ballandras-Colas A, Chivukula V, Gruszka DT, Shan Z, Singh PK, Pye VE, McLean RK, Bedwell GJ, Li W, Nans A, Cook NJ, Fadel HJ, Poeschla EM, Griffiths DJ, Vargas J, Taylor IA, Lyumkis D, Yardimci H, Engelman AN, Cherepanov P. Ballandras-Colas A, et al. Among authors: shan z. Nat Commun. 2022 May 3;13(1):2416. doi: 10.1038/s41467-022-29928-8. Nat Commun. 2022. PMID: 35504909 Free PMC article.
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR Jr, Levy RM, Hughes SH, Craigie R, Lyumkis D. Li M, et al. Among authors: shan z. Sci Adv. 2023 Jul 21;9(29):eadg5953. doi: 10.1126/sciadv.adg5953. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478179 Free article.
Overcoming resolution attenuation during tilted cryo-EM data collection.
Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Aiyer S, et al. Among authors: shan z. Nat Commun. 2024 Jan 9;15(1):389. doi: 10.1038/s41467-023-44555-7. Nat Commun. 2024. PMID: 38195598 Free PMC article.
Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection.
Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Aiyer S, et al. Among authors: shan z. bioRxiv [Preprint]. 2023 Jul 15:2023.07.14.548955. doi: 10.1101/2023.07.14.548955. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 9;15(1):389. doi: 10.1038/s41467-023-44555-7 PMID: 37503021 Free PMC article. Updated. Preprint.
1,803 results