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Machine learning for target discovery in drug development.
Rodrigues T, Bernardes GJL. Rodrigues T, et al. Among authors: bernardes gjl. Curr Opin Chem Biol. 2020 Jun;56:16-22. doi: 10.1016/j.cbpa.2019.10.003. Epub 2019 Nov 14. Curr Opin Chem Biol. 2020. PMID: 31734566 Review.
Selective Inhibition of Bruton's Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors.
Sousa BB, de Almeida CR, Barahona AF, Lopes R, Martins-Logrado A, Cavaco M, Neves V, Carvalho LAR, Labão-Almeida C, Coelho AR, Leal Bento M, Lopes RMRM, Oliveira BL, Castanho MARB, Neumeister P, Deutsch A, Vladimer GI, Krall N, João C, Corzana F, Seixas JD, Fior R, Bernardes GJL. Sousa BB, et al. Among authors: bernardes gjl. ACS Pharmacol Transl Sci. 2022 Nov 2;5(11):1156-1168. doi: 10.1021/acsptsci.2c00163. eCollection 2022 Nov 11. ACS Pharmacol Transl Sci. 2022. PMID: 36407952 Free PMC article.
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.
Pena AC, Penacho N, Mancio-Silva L, Neres R, Seixas JD, Fernandes AC, Romão CC, Mota MM, Bernardes GJ, Pamplona A. Pena AC, et al. Antimicrob Agents Chemother. 2012 Mar;56(3):1281-90. doi: 10.1128/AAC.05571-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155828 Free PMC article.
186 results