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Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe. Ouedraogo G, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2022 Jul;132:105161. doi: 10.1016/j.yrtph.2022.105161. Epub 2022 May 1. Regul Toxicol Pharmacol. 2022. PMID: 35508214 Free article.
Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.
Blackburn K, Bjerke D, Daston G, Felter S, Mahony C, Naciff J, Robison S, Wu S. Blackburn K, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2011 Jun;60(1):120-35. doi: 10.1016/j.yrtph.2011.03.002. Epub 2011 Mar 21. Regul Toxicol Pharmacol. 2011. PMID: 21420459
The SEURAT-1 approach towards animal free human safety assessment.
Gocht T, Berggren E, Ahr HJ, Cotgreave I, Cronin MT, Daston G, Hardy B, Heinzle E, Hescheler J, Knight DJ, Mahony C, Peschanski M, Schwarz M, Thomas RS, Verfaillie C, White A, Whelan M. Gocht T, et al. Among authors: mahony c. ALTEX. 2015;32(1):9-24. doi: 10.14573/altex.1408041. Epub 2014 Nov 5. ALTEX. 2015. PMID: 25372315 Free article.
A strategy for structuring and reporting a read-across prediction of toxicity.
Schultz TW, Amcoff P, Berggren E, Gautier F, Klaric M, Knight DJ, Mahony C, Schwarz M, White A, Cronin MT. Schultz TW, et al. Among authors: mahony c. Regul Toxicol Pharmacol. 2015 Aug;72(3):586-601. doi: 10.1016/j.yrtph.2015.05.016. Epub 2015 May 21. Regul Toxicol Pharmacol. 2015. PMID: 26003513 Free article.
A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.
Desprez B, Dent M, Keller D, Klaric M, Ouédraogo G, Cubberley R, Duplan H, Eilstein J, Ellison C, Grégoire S, Hewitt NJ, Jacques-Jamin C, Lange D, Roe A, Rothe H, Blaauboer BJ, Schepky A, Mahony C. Desprez B, et al. Among authors: mahony c. Toxicol In Vitro. 2018 Aug;50:137-146. doi: 10.1016/j.tiv.2018.02.017. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29499337 Review.
A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.
Desprez B, Birk B, Blaauboer B, Boobis A, Carmichael P, Cronin MTD, Curie R, Daston G, Hubesch B, Jennings P, Klaric M, Kroese D, Mahony C, Ouédraogo G, Piersma A, Richarz AN, Schwarz M, van Benthem J, van de Water B, Vinken M. Desprez B, et al. Among authors: mahony c. Toxicol In Vitro. 2019 Sep;59:44-50. doi: 10.1016/j.tiv.2019.04.005. Epub 2019 Apr 4. Toxicol In Vitro. 2019. PMID: 30954655
New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop.
Mahony C, Ashton RS, Birk B, Boobis AR, Cull T, Daston GP, Ewart L, Knudsen TB, Manou I, Maurer-Stroh S, Margiotta-Casaluci L, Müller BP, Nordlund P, Roberts RA, Steger-Hartmann T, Vandenbossche E, Viant MR, Vinken M, Whelan M, Zvonimir Z, Cronin MTD. Mahony C, et al. Regul Toxicol Pharmacol. 2020 Jul;114:104668. doi: 10.1016/j.yrtph.2020.104668. Epub 2020 Apr 23. Regul Toxicol Pharmacol. 2020. PMID: 32335207 Free article.
235 results