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Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasini E, Saftig P, Schweizer M, Svergun D, Amin L, Mazzola F, Varani L, Thapa S, Gilch S, Schätzl H, Harris DA, Triller A, Mikhaylova M, Aguzzi A, Altmeppen HC, Glatzel M. Linsenmeier L, et al. Among authors: song f. Sci Adv. 2021 Nov 26;7(48):eabj1826. doi: 10.1126/sciadv.abj1826. Epub 2021 Nov 24. Sci Adv. 2021. PMID: 34818048 Free PMC article.
Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases.
Song F, Kovac V, Mohammadi B, Littau JL, Scharfenberg F, Matamoros Angles A, Vanni I, Shafiq M, Orge L, Galliciotti G, Djakkani S, Linsenmeier L, Černilec M, Hartman K, Jung S, Tatzelt J, Neumann JE, Damme M, Tschirner SK, Lichtenthaler SF, Ricklefs FL, Sauvigny T, Schmitz M, Zerr I, Puig B, Tolosa E, Ferrer I, Magnus T, Rupnik MS, Sepulveda-Falla D, Matschke J, Šmid LM, Bresjanac M, Andreoletti O, Krasemann S, Foliaki ST, Nonno R, Becker-Pauly C, Monzo C, Crozet C, Haigh CL, Glatzel M, Curin Serbec V, Altmeppen HC. Song F, et al. Acta Neuropathol. 2024 Jul 9;148(1):2. doi: 10.1007/s00401-024-02763-5. Acta Neuropathol. 2024. PMID: 38980441 Free PMC article.
Efficient enzyme-free isolation of brain-derived extracellular vesicles.
Matamoros-Angles A, Karadjuzovic E, Mohammadi B, Song F, Brenna S, Meister SC, Siebels B, Voß H, Seuring C, Ferrer I, Schlüter H, Kneussel M, Altmeppen HC, Schweizer M, Puig B, Shafiq M, Glatzel M. Matamoros-Angles A, et al. Among authors: song f. J Extracell Vesicles. 2024 Nov;13(11):e70011. doi: 10.1002/jev2.70011. J Extracell Vesicles. 2024. PMID: 39508423 Free PMC article.
Protein PARylation: a novel regulator of fungal virulence.
Wang J, Yan Y, Song F. Wang J, et al. Among authors: song f. Trends Microbiol. 2024 Dec 24:S0966-842X(24)00320-2. doi: 10.1016/j.tim.2024.12.003. Online ahead of print. Trends Microbiol. 2024. PMID: 39721911
4,248 results