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Biallelic HFM1 variants cause non-obstructive azoospermia with meiotic arrest in humans by impairing crossover formation to varying degrees.
Xie X, Murtaza G, Li Y, Zhou J, Ye J, Khan R, Jiang L, Khan I, Zubair M, Yin H, Jiang H, Liu W, Shi B, Hou X, Gong C, Fan S, Wang Y, Jiang X, Zhang Y, Zhang H, Ma H, Shi Q. Xie X, et al. Among authors: khan r, khan i. Hum Reprod. 2022 Jun 30;37(7):1664-1677. doi: 10.1093/humrep/deac092. Hum Reprod. 2022. PMID: 35526155
The deubiquitinating gene Usp29 is dispensable for fertility in male mice.
Huang Z, Khan M, Xu J, Khan T, Ma H, Khan R, Hussain HMJ, Jiang X, Shi Q. Huang Z, et al. Among authors: khan r, khan t, khan m. Sci China Life Sci. 2019 Apr;62(4):544-552. doi: 10.1007/s11427-018-9469-4. Epub 2019 Mar 22. Sci China Life Sci. 2019. PMID: 30919279
Whole Exome Sequencing Revealed a Novel Nonsense Variant in the GNRHR Gene Causing Normosmic Hypogonadotropic Hypogonadism in a Pakistani Family.
Hussain HMJ, Murtaza G, Jiang X, Khan R, Khan M, Kakakhel MBS, Khan T, Wahab F, Zhang H, Zhang Y, Khan MB, Ahmed P, Ma H, Xu Z. Hussain HMJ, et al. Among authors: khan r, khan t, khan mb, khan m. Horm Res Paediatr. 2019;91(1):9-16. doi: 10.1159/000497114. Epub 2019 Apr 4. Horm Res Paediatr. 2019. PMID: 30947225 Clinical Trial.
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q. Zhang B, et al. Among authors: khan r, khan t, khan i. J Exp Med. 2020 Feb 3;217(2):e20182365. doi: 10.1084/jem.20182365. J Exp Med. 2020. PMID: 31658987 Free PMC article.
4,945 results