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Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques.
Zabaleta N, Bhatt U, Hérate C, Maisonnasse P, Sanmiguel J, Diop C, Castore S, Estelien R, Li D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Pascal Q, Naninck T, Kahlaoui N, Lemaitre J, Relouzat F, Ronzitti G, Thibaut HJ, Montomoli E, Wilson JM, Le Grand R, Vandenberghe LH. Zabaleta N, et al. Mol Ther. 2022 Sep 7;30(9):2952-2967. doi: 10.1016/j.ymthe.2022.05.007. Epub 2022 May 10. Mol Ther. 2022. PMID: 35546782 Free PMC article.
MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques.
Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, Augustijns P, Bouchemal K, Ponchel G, Ramos OH, Herrera C, Stefanidou M, Shattock R, Heyndrickx L, Vanham G, Kessler P, Le Grand R, Martin L. Dereuddre-Bosquet N, et al. PLoS Pathog. 2012;8(12):e1003071. doi: 10.1371/journal.ppat.1003071. Epub 2012 Dec 6. PLoS Pathog. 2012. PMID: 23236282 Free PMC article.
Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses.
Bruel T, Hamimi C, Dereuddre-Bosquet N, Cosma A, Shin SY, Corneau A, Versmisse P, Karlsson I, Malleret B, Targat B, Barré-Sinoussi F, Le Grand R, Pancino G, Sáez-Cirión A, Vaslin B. Bruel T, et al. J Virol. 2015 Apr;89(7):3542-56. doi: 10.1128/JVI.03723-14. Epub 2015 Jan 14. J Virol. 2015. PMID: 25589645 Free PMC article.
Intradermal injection of an anti-Langerin-HIVGag fusion vaccine targets epidermal Langerhans cells in nonhuman primates and can be tracked in vivo.
Salabert N, Todorova B, Martinon F, Boisgard R, Zurawski G, Zurawski S, Dereuddre-Bosquet N, Cosma A, Kortulewski T, Banchereau J, Levy Y, Le Grand R, Chapon C. Salabert N, et al. Eur J Immunol. 2016 Mar;46(3):689-700. doi: 10.1002/eji.201545465. Epub 2016 Jan 19. Eur J Immunol. 2016. PMID: 26678013 Free article.
155 results