Sim T - Search Results

1

AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis.

Kim H, Jeong M, Na DH, Ryu SH, Jeong EI, Jung K, Kang J, Lee HJ, Sim T, Yu DY, Yu HC, Cho BH, Jung YK. Kim H, et al. Among authors: sim t. Cell Death Dis. 2022 May 18;13(5):469. doi: 10.1038/s41419-022-04921-7. Cell Death Dis. 2022. PMID: 35585049 Free PMC article.

2

Novel small molecule Raf kinase inhibitors for targeted cancer therapeutics.

Kim DH, Sim T. Kim DH, et al. Among authors: sim t. Arch Pharm Res. 2012 Mar;35(4):605-15. doi: 10.1007/s12272-012-0403-5. Epub 2012 May 3. Arch Pharm Res. 2012. PMID: 22553052 Review.

3

ROS1 Kinase Inhibitors for Molecular-Targeted Therapies.

Al-Sanea MM, Abdelazem AZ, Park BS, Yoo KH, Sim T, Kwon YJ, Lee SH. Al-Sanea MM, et al. Among authors: sim t. Curr Med Chem. 2016;23(2):142-60. doi: 10.2174/0929867322666151006093623. Curr Med Chem. 2016. PMID: 26438251 Review.

4

Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.

Yoon H, Shin I, Nam Y, Kim ND, Lee KB, Sim T. Yoon H, et al. Among authors: sim t. Eur J Med Chem. 2017 Jan 5;125:1145-1155. doi: 10.1016/j.ejmech.2016.10.050. Epub 2016 Oct 22. Eur J Med Chem. 2017. PMID: 27814560

5

Suppression of TRPM7 enhances TRAIL-induced apoptosis in triple-negative breast cancer cells.

Song C, Choi S, Oh KB, Sim T. Song C, et al. Among authors: sim t. J Cell Physiol. 2020 Dec;235(12):10037-10050. doi: 10.1002/jcp.29820. Epub 2020 May 29. J Cell Physiol. 2020. PMID: 32468675

6

The first small molecules capable of strongly suppressing proliferation of cancer cells harboring BRAF class I/II/III mutations.

Choi SH, Shin I, Kim N, Nam Y, Sim T. Choi SH, et al. Among authors: sim t. Biochem Biophys Res Commun. 2020 Nov 5;532(2):315-320. doi: 10.1016/j.bbrc.2020.07.110. Epub 2020 Aug 30. Biochem Biophys Res Commun. 2020. PMID: 32873393

7

Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance.

Kim N, Shin I, Lee J, Jeon E, Kim Y, Ryu S, Ju E, Cho W, Sim T. Kim N, et al. Among authors: sim t. Int J Mol Sci. 2021 Apr 6;22(7):3783. doi: 10.3390/ijms22073783. Int J Mol Sci. 2021. PMID: 33917428 Free PMC article.

8

Novel quinolinylaminoisoquinoline bioisosteres of sorafenib as selective RAF1 kinase inhibitors: design, synthesis, and antiproliferative activity against melanoma cell line.

Cho HJ, El-Gamal MI, Oh CH, Lee SH, Sim T, Kim G, Choi HS, Choi JH, Yoo KH. Cho HJ, et al. Among authors: sim t. Chem Pharm Bull (Tokyo). 2013;61(7):747-56. doi: 10.1248/cpb.c13-00283. Chem Pharm Bull (Tokyo). 2013. PMID: 23812399 Free article.

9

Identification of methyl violet 2B as a novel blocker of focal adhesion kinase signaling pathway in cancer cells.

Kim H, Kim ND, Lee J, Han G, Sim T. Kim H, et al. Among authors: sim t. Biochem Biophys Res Commun. 2013 Jul 26;437(2):319-24. doi: 10.1016/j.bbrc.2013.06.078. Epub 2013 Jun 28. Biochem Biophys Res Commun. 2013. PMID: 23817042

10

Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors.

Park BS, Al-Sanea MM, Abdelazem AZ, Park HM, Roh EJ, Park HM, Yoo KH, Sim T, Tae JS, Lee SH. Park BS, et al. Among authors: sim t. Bioorg Med Chem. 2014 Aug 1;22(15):3871-8. doi: 10.1016/j.bmc.2014.06.020. Epub 2014 Jun 18. Bioorg Med Chem. 2014. PMID: 24997577

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