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Reversible lysine-targeted probes reveal residence time-based kinase selectivity.
Yang T, Cuesta A, Wan X, Craven GB, Hirakawa B, Khamphavong P, May JR, Kath JC, Lapek JD Jr, Niessen S, Burlingame AL, Carelli JD, Taunton J. Yang T, et al. Nat Chem Biol. 2022 Sep;18(9):934-941. doi: 10.1038/s41589-022-01019-1. Epub 2022 May 19. Nat Chem Biol. 2022. PMID: 35590003 Free PMC article.
Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking.
Wan X, Yang T, Cuesta A, Pang X, Balius TE, Irwin JJ, Shoichet BK, Taunton J. Wan X, et al. Among authors: yang t. J Am Chem Soc. 2020 Mar 18;142(11):4960-4964. doi: 10.1021/jacs.9b10377. Epub 2020 Mar 4. J Am Chem Soc. 2020. PMID: 32105459 Free PMC article.
A chemical probe for lysine malonylation.
Bao X, Zhao Q, Yang T, Fung YM, Li XD. Bao X, et al. Among authors: yang t. Angew Chem Int Ed Engl. 2013 Apr 26;52(18):4883-6. doi: 10.1002/anie.201300252. Epub 2013 Mar 26. Angew Chem Int Ed Engl. 2013. PMID: 23533089 No abstract available.
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