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Page 1
Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
Zhu K, Wang Y, Sarlus H, Geng K, Nutma E, Sun J, Kung SY, Bay C, Han J, Min JH, Benito-Cuesta I, Lund H, Amor S, Wang J, Zhang XM, Kutter C, Guerreiro-Cacais AO, Högberg B, Harris RA. Zhu K, et al. Among authors: guerreiro cacais ao. EMBO Rep. 2022 Jul 5;23(7):e54499. doi: 10.15252/embr.202154499. Epub 2022 May 20. EMBO Rep. 2022. PMID: 35593064 Free PMC article.
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.
Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. Lund H, et al. Nat Immunol. 2018 May;19(5):1-7. doi: 10.1038/s41590-018-0091-5. Epub 2018 Apr 16. Nat Immunol. 2018. PMID: 29662171 Free PMC article.
C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation.
N'diaye M, Brauner S, Flytzani S, Kular L, Warnecke A, Adzemovic MZ, Piket E, Min JH, Edwards W, Mela F, Choi HY, Magg V, James T, Linden M, Reichardt HM, Daws MR, van Horssen J, Kockum I, Harris RA, Olsson T, Guerreiro-Cacais AO, Jagodic M. N'diaye M, et al. Among authors: guerreiro cacais ao. J Clin Invest. 2020 Feb 3;130(2):838-852. doi: 10.1172/JCI125857. J Clin Invest. 2020. PMID: 31725411 Free PMC article.
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.
Falcão AM, van Bruggen D, Marques S, Meijer M, Jäkel S, Agirre E, Samudyata, Floriddia EM, Vanichkina DP, Ffrench-Constant C, Williams A, Guerreiro-Cacais AO, Castelo-Branco G. Falcão AM, et al. Nat Med. 2018 Dec;24(12):1837-1844. doi: 10.1038/s41591-018-0236-y. Epub 2018 Nov 12. Nat Med. 2018. PMID: 30420755 Free PMC article.
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.
Bronge M, Högelin KA, Thomas OG, Ruhrmann S, Carvalho-Queiroz C, Nilsson OB, Kaiser A, Zeitelhofer M, Holmgren E, Linnerbauer M, Adzemovic MZ, Hellström C, Jelcic I, Liu H, Nilsson P, Hillert J, Brundin L, Fink K, Kockum I, Tengvall K, Martin R, Tegel H, Gräslund T, Al Nimer F, Guerreiro-Cacais AO, Khademi M, Gafvelin G, Olsson T, Grönlund H. Bronge M, et al. Among authors: guerreiro cacais ao. Sci Adv. 2022 Apr 29;8(17):eabn1823. doi: 10.1126/sciadv.abn1823. Epub 2022 Apr 27. Sci Adv. 2022. PMID: 35476434 Free PMC article.
Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis.
Thomas OG, Bronge M, Tengvall K, Akpinar B, Nilsson OB, Holmgren E, Hessa T, Gafvelin G, Khademi M, Alfredsson L, Martin R, Guerreiro-Cacais AO, Grönlund H, Olsson T, Kockum I. Thomas OG, et al. Among authors: guerreiro cacais ao. Sci Adv. 2023 May 19;9(20):eadg3032. doi: 10.1126/sciadv.adg3032. Epub 2023 May 17. Sci Adv. 2023. PMID: 37196088 Free PMC article.
32 results