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Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
Zhu K, Wang Y, Sarlus H, Geng K, Nutma E, Sun J, Kung SY, Bay C, Han J, Min JH, Benito-Cuesta I, Lund H, Amor S, Wang J, Zhang XM, Kutter C, Guerreiro-Cacais AO, Högberg B, Harris RA. Zhu K, et al. Among authors: kutter c. EMBO Rep. 2022 Jul 5;23(7):e54499. doi: 10.15252/embr.202154499. Epub 2022 May 20. EMBO Rep. 2022. PMID: 35593064 Free PMC article.
CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.
Søndergaard JN, Sommerauer C, Atanasoai I, Hinte LC, Geng K, Guiducci G, Bräutigam L, Aouadi M, Stojic L, Barragan I, Kutter C. Søndergaard JN, et al. Among authors: kutter c. Gut. 2022 Jan 12;71(10):2081-92. doi: 10.1136/gutjnl-2021-325109. Online ahead of print. Gut. 2022. PMID: 35022268 Free PMC article.
Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription.
Cameron DP, Grosser J, Ladigan S, Kuzin V, Iliopoulou E, Wiegard A, Benredjem H, Jackson K, Liffers ST, Lueong S, Cheung PF, Vangala D, Pohl M, Viebahn R, Teschendorf C, Wolters H, Usta S, Geng K, Kutter C, Arsenian-Henriksson M, Siveke JT, Tannapfel A, Schmiegel W, Hahn SA, Baranello L. Cameron DP, et al. Among authors: kutter c. Sci Adv. 2023 Oct 13;9(41):eadg5109. doi: 10.1126/sciadv.adg5109. Epub 2023 Oct 13. Sci Adv. 2023. PMID: 37831776 Free PMC article.
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Nørskov Søndergaard J, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke VM, Archer A, Williams C, Kutter C. Sommerauer C, et al. Among authors: kutter c. Mol Syst Biol. 2024 Apr;20(4):374-402. doi: 10.1038/s44320-024-00024-x. Epub 2024 Mar 8. Mol Syst Biol. 2024. PMID: 38459198 Free PMC article.
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.
Blanco S, Dietmann S, Flores JV, Hussain S, Kutter C, Humphreys P, Lukk M, Lombard P, Treps L, Popis M, Kellner S, Hölter SM, Garrett L, Wurst W, Becker L, Klopstock T, Fuchs H, Gailus-Durner V, Hrabĕ de Angelis M, Káradóttir RT, Helm M, Ule J, Gleeson JG, Odom DT, Frye M. Blanco S, et al. Among authors: kutter c. EMBO J. 2014 Sep 17;33(18):2020-39. doi: 10.15252/embj.201489282. Epub 2014 Jul 25. EMBO J. 2014. PMID: 25063673 Free PMC article.
72 results