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Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.
Schad SE, Chow A, Mangarin L, Pan H, Zhang J, Ceglia N, Caushi JX, Malandro N, Zappasodi R, Gigoux M, Hirschhorn D, Budhu S, Amisaki M, Arniella M, Redmond D, Chaft J, Forde PM, Gainor JF, Hellmann MD, Balachandran V, Shah S, Smith KN, Pardoll D, Elemento O, Wolchok JD, Merghoub T. Schad SE, et al. Among authors: pan h. J Exp Med. 2022 Jun 6;219(6):e20212169. doi: 10.1084/jem.20212169. Epub 2022 May 23. J Exp Med. 2022. PMID: 35604411 Free PMC article.
Epigenomic evolution in diffuse large B-cell lymphomas.
Pan H, Jiang Y, Boi M, Tabbò F, Redmond D, Nie K, Ladetto M, Chiappella A, Cerchietti L, Shaknovich R, Melnick AM, Inghirami GG, Tam W, Elemento O. Pan H, et al. Nat Commun. 2015 Apr 20;6:6921. doi: 10.1038/ncomms7921. Nat Commun. 2015. PMID: 25891015 Free PMC article.
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, Hother C, Liu S, Cao XJ, Tam W, Shaknovich R, Garcia BA, Gascoyne RD, Ge K, Shilatifard A, Elemento O, Nussenzweig A, Melnick AM, Wendel HG. Ortega-Molina A, et al. Among authors: pan h. Nat Med. 2015 Oct;21(10):1199-208. doi: 10.1038/nm.3943. Epub 2015 Sep 14. Nat Med. 2015. PMID: 26366710 Free PMC article.
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.
Dalton T, Doubrovina E, Pankov D, Reynolds R, Scholze H, Selvakumar A, Vizconde T, Savalia B, Dyomin V, Weigel C, Oakes CC, Alonso A, Elemento O, Pan H, Phillip JM, O'Reilly RJ, Gewurz BE, Cesarman E, Giulino-Roth L. Dalton T, et al. Among authors: pan h. Blood. 2020 May 21;135(21):1870-1881. doi: 10.1182/blood.2019004126. Blood. 2020. PMID: 32157281 Free PMC article.
CIC is a critical regulator of neuronal differentiation.
Hwang I, Pan H, Yao J, Elemento O, Zheng H, Paik J. Hwang I, et al. Among authors: pan h. JCI Insight. 2020 May 7;5(9):e135826. doi: 10.1172/jci.insight.135826. JCI Insight. 2020. PMID: 32229723 Free PMC article.
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Liu D, Shoag JE, Poliak D, Goueli RS, Ravikumar V, Redmond D, Vosoughi A, Fontugne J, Pan H, Lee D, Thomas D, Salari K, Wang Z, Romanel A, Te A, Lee R, Chughtai B, Olumi AF, Mosquera JM, Demichelis F, Elemento O, Rubin MA, Sboner A, Barbieri CE. Liu D, et al. Among authors: pan h. Nat Commun. 2020 Apr 24;11(1):1987. doi: 10.1038/s41467-020-15913-6. Nat Commun. 2020. PMID: 32332823 Free PMC article.
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